Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133635 | 0.69 | P2RX4 (0.41) | APEX1CA12CA9LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL3122652 | 0.68 | P2RX4 (0.40) | ALDH1A1APEX1CA12CA9LMNA | |
| SCHEMBL5066904 | 0.68 | SMN1; SMN2 (0.38) | APEX1CA12CA9SMN1; SMN2L3MBTL1 | |
| SCHEMBL7501140 | 0.68 | SMN1; SMN2 (0.38) | APEX1CA12CA9SMN1; SMN2L3MBTL1 | |
| SCHEMBL8039840 | 0.65 | GLA (0.33) | APEX1CA12CA9LMNAKDM4E | |
| SCHEMBL515800 | 0.64 | PTGS1 (0.52) | ALDH1A1HPGDHSD17B10CA12CA9 | |
| Hydrochloric Acid SCHEMBL28991159 | 0.63 | PTGS1 (0.50) | ALDH1A1HPGDHSD17B10CA12CA9 | |
| Ethylene Glycol SCHEMBL28669577 | 0.60 | PTGS1 (0.47) | ALDH1A1HPGDHSD17B10CA12CA9 | |
| Alcohol SCHEMBL29133233 | 0.58 | GSK3A (0.55) | ALDH1A1HPGDCA12CA9LMNA | |
| SCHEMBL6207618 | 0.57 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1084849-A | Dual action inhibitors | SQUIBB & SONS INC (US) | 1994-04-06 | — | — | CN | disclosed |