Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | AGER | Q15109 | 4/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5070302 | 0.84 | CETP (0.40) | MAOBBCHEACHE | |
| SCHEMBL729448 | 0.84 | AGER (0.40) | NPC1TSHRRAB9AAGERBCHE | |
| SCHEMBL5067350 | 0.83 | RAB9A (0.43) | NPC1TSHRRAB9AAGERBCHE | |
| SCHEMBL727538 | 0.75 | HRH3 (0.45) | BCHEACHE | |
| SCHEMBL729132 | 0.73 | AGER (0.39) | AGER | |
| SCHEMBL5069474 | 0.72 | BMPR1B (0.40) | MAOBNPC1RAB9ABCHEACHE | |
| SCHEMBL729430 | 0.72 | TRPV4 (0.39) | AGER | |
| SCHEMBL727888 | 0.72 | AGER (0.40) | AGER | |
| SCHEMBL1779706 | 0.72 | HRH3 (0.59) | — | |
| SCHEMBL727562 | 0.72 | AGER (0.38) | NPC1RAB9AAGER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979334-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Dong Wha Pharmaceutical. Ind. Co., Ltd. (KR) | 2008-10-15 | — | — | EP | claimed |
| WO-2007089101-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONG WHA PHARMACEUTICAL IND.CO., LTD. (KR) | 2007-08-09 | — | — | WO | claimed |