Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.53 |
| ▸ | TUBB | P07437 | 3/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4573958 | 0.90 | KDM4E (0.54) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL4720481 | 0.86 | GAA (0.71) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL6669145 | 0.83 | HCRTR1 (0.56) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL25263341 | 0.83 | GAA (0.54) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL6669594 | 0.82 | GABRA1 (0.64) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL14829996 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL31451652 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL2390518 | 0.81 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL19322277 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL28026395 | 0.81 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080302674-A1 | Probe Unit, Apparatus for Identifying Nucleotide Region and Method of Identifying Nucleotide Region | KYOTO UNIVERSITY (JP) | 2008-12-11 | — | — | US | disclosed |
| EP-1830183-A1 | PROBE UNIT, APPARATUS FOR IDENTIFYING NUCLEOTIDE REGION AND METHOD OF IDENTIFYING NUCLEOTIDE REGION | Kyoto University (JP) | 2007-09-05 | — | — | EP | disclosed |
| US-6596726-B1 | Method of inhibiting epidermal growth factor by treating, with an effective inhibiting amount, a mammal, in need thereof inhibit the epidermal growth factor receptor and related receptors and, in particular, their tyrosine kinase enzyme | WARNER LAMBERT COMPANY | 2003-07-22 | — | — | US | disclosed |
| US-5679683-A | USEFUL FOR TREATING CANCER, ARTHRITIS, PSORIASIS, VASCULAR RESTENOSIS AND ANGIOGENESIS | WARNER-LAMBERT COMPANY (US) | 1997-10-21 | — | — | US | disclosed |
| EP-0741711-A1 | TRICYCLIC COMPOUNDS CAPABLE OF INHIBITING TYROSINE KINASES OF THE EPIDERMAL GROWTH FACTOR RECEPTOR FAMILY | WARNER-LAMBERT COMPANY (US) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995019970-A1 | TRICYCLIC COMPOUNDS CAPABLE OF INHIBITING TYROSINE KINASES OF THE EPIDERMAL GROWTH FACTOR RECEPTOR FAMILY | WARNER-LAMBERT COMPANY (US) | 1995-07-27 | — | — | WO | disclosed |