Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3214133 | 0.98 | APP (0.41) | APPSNCATNFNOD1MEN1 | |
| SCHEMBL3643981 | 0.97 | APP (0.42) | APPSNCATNFNOD1MEN1 | |
| SCHEMBL5716206 | 0.93 | APP (0.38) | APPSNCATNFNOD1MEN1 | |
| SCHEMBL7049507 | 0.88 | SMN1; SMN2 (0.45) | APPSNCATNFNOD1MEN1 | |
| SCHEMBL4625707 | 0.84 | SNCA (0.50) | APPSNCATNFNOD1MEN1 | |
| SCHEMBL28755569 | 0.80 | INSR (0.44) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL3217539 | 0.79 | — | — | |
| SCHEMBL7050705 | 0.74 | ALDH1A1 (0.47) | APPSNCATNFNOD1MEN1 | |
| SCHEMBL2028552 | 0.74 | SNCA (0.41) | APPSNCATNFNOD1MEN1 | |
| SCHEMBL7049508 | 0.72 | APP (0.33) | APPSNCATNFNOD1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433469-A1 | Composition for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | claimed |
| EP-1875892-A2 | Brightening and/or dyeing agent containing pyrazoles | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-01-09 | — | — | EP | disclosed |