Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4382272 | 0.86 | MAOA (0.49) | PIN1SMN1; SMN2VCAM1GPR84MAOA | |
| SCHEMBL4976601 | 0.86 | GPR84 (0.46) | PIN1SMN1; SMN2VCAM1GPR84MAOA | |
| SCHEMBL810842 | 0.86 | MEN1 (0.53) | PIN1SMN1; SMN2VCAM1MAOAMAOB | |
| SCHEMBL29463873 | 0.86 | MEN1 (0.53) | PIN1SMN1; SMN2VCAM1MAOAMAOB | |
| SCHEMBL18702745 | 0.83 | CA12 (0.50) | PIN1CYP11B1CYP11B2MAOAMAOB | |
| SCHEMBL29502991 | 0.83 | MAPT (0.51) | PIN1SMN1; SMN2CYP11B1CYP11B2MAOA | |
| SCHEMBL18702665 | 0.83 | MAPT (0.51) | PIN1SMN1; SMN2CYP11B1CYP11B2MAOA | |
| SCHEMBL4976607 | 0.82 | GPR84 (0.41) | SMN1; SMN2VCAM1GPR84NPC1RAB9A | |
| SCHEMBL7206840 | 0.81 | MAPT (0.47) | VCAM1 | |
| SCHEMBL8127404 | 0.81 | KDM4E (0.59) | SMN1; SMN2CYP11B1CYP11B2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971611-B1 | ANTI-VIRAL COMPOUNDS | ABBOTT LAB (US) | 2012-10-10 | — | — | EP | disclosed |
| EP-1971611-A1 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007081517-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-19 | — | — | WO | disclosed |