Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810907 | 0.87 | PARP10 (0.46) | PDE7AVCAM1ALDH1A1MAPTMAPK1 | |
| SCHEMBL5067747 | 0.82 | PIN1 (0.54) | GPR84VCAM1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4382272 | 0.80 | MAOA (0.49) | GPR84VCAM1ALDH1A1MAPTMAPK1 | |
| SCHEMBL4976601 | 0.79 | GPR84 (0.46) | GPR84SIRT2VCAM1MAPTMAPK1 | |
| SCHEMBL14328006 | 0.79 | DRD2 (0.52) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL7206840 | 0.77 | MAPT (0.47) | VCAM1ALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL14290088 | 0.76 | MAPT (0.64) | VCAM1ALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL5458467 | 0.76 | VCAM1 (0.49) | VCAM1ALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL9513657 | 0.76 | MAPT (0.56) | VCAM1ALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL9524443 | 0.75 | VCAM1 (0.48) | PDE7AVCAM1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| EP-1971611-A1 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007081517-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-19 | — | — | WO | disclosed |
| WO-2007076034-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |