Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CCR1 | P32246 | 3/20 | 0.51 |
| ▸ | CCR5 | P51681 | 3/20 | 0.51 |
| ▸ | CCR8 | P51685 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12655926 | 0.88 | KDM4E (0.51) | KDM4ESMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL12655942 | 0.83 | KDM4E (0.71) | KDM4ESMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL31282814 | 0.83 | KDM4E (0.71) | KDM4ESMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL18078699 | 0.81 | SMN1; SMN2 (0.51) | KDM4ESMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL12655927 | 0.81 | KDM4E (0.46) | KDM4ESMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL19219089 | 0.81 | SMN1; SMN2 (0.54) | KDM4ESMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL30596386 | 0.80 | KDM4E (0.61) | KDM4ESMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL29575458 | 0.80 | KDM4E (0.65) | KDM4ESMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL36011 | 0.80 | KDM4E (0.61) | KDM4ESMN1; SMN2ALDH1A1HPGDGAA | |
| SCHEMBL12655952 | 0.80 | MAPT (0.46) | KDM4ESMN1; SMN2ALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383553-B2 | Dyes | MERCK PATENT GMBH (DE) | 2013-02-26 | — | — | US | disclosed |
| US-8383553-B2 | Dyes | MERCK PATENT GMBH (DE) | 2013-02-26 | — | — | US | disclosed |
| US-8064119-B2 | Display element and driving method thereof | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-11-22 | — | — | US | disclosed |
| US-8064119-B2 | Display element and driving method thereof | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-11-22 | — | — | US | disclosed |
| US-20110058244-A1 | ELECTROCHROMIC DISPLAY ELEMENT | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-03-10 | — | — | US | disclosed |
| US-20110058244-A1 | ELECTROCHROMIC DISPLAY ELEMENT | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-03-10 | — | — | US | disclosed |
| US-20100091352-A1 | DISPLAY ELEMENT AND DRIVING METHOD THEREOF | KONICA MINOLTA HOLDINGS, INC. (JP) | 2010-04-15 | — | — | US | disclosed |
| US-20100091352-A1 | DISPLAY ELEMENT AND DRIVING METHOD THEREOF | KONICA MINOLTA HOLDINGS, INC. (JP) | 2010-04-15 | — | — | US | disclosed |
| WO-2009055183-A2 | NOVEL DYES | KONARKA TECHNOLOGIES, INC. (US) | 2009-04-30 | — | — | WO | disclosed |
| US-20090107552-A1 | Novel Dyes | MERCK KGAA (DE) | 2009-04-30 | — | — | US | disclosed |
| US-20090107552-A1 | Novel Dyes | MERCK KGAA (DE) | 2009-04-30 | — | — | US | disclosed |
| US-7465747-B2 | Fluorescent label compounds | Matsumoto, Kazuko (JP) | 2008-12-16 | — | — | US | disclosed |
| US-7465747-B2 | Fluorescent label compounds | Matsumoto, Kazuko (JP) | 2008-12-16 | — | — | US | disclosed |
| US-7465747-B2 | Fluorescent label compounds | Matsumoto, Kazuko (JP) | 2008-12-16 | — | — | US | disclosed |
| US-20050255465-A1 | Novel fluorescent label compounds | KAZUKO MATSUMOTO (JP) | 2005-11-17 | — | — | US | disclosed |
| EP-1489418-A1 | NOVEL FLUORESCENT LABEL COMPOUNDS | Matsumoto, Kazuko (JP) | 2004-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050255465-A1 | Novel fluorescent label compounds | TRPC6, CHERP, FIBP | KDM4E 4389/4885SMN1; SMN2 3231/4885ALDH1A1 543/4885 |
| US-20090107552-A1 | Novel Dyes | CRY2, CRY1, HCCS | KDM4E 2975/4885SMN1; SMN2 4851/4885ALDH1A1 1538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.