Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702087 | 0.86 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7940214 | 0.86 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL64874 | 0.85 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL35612 | 0.84 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL35807 | 0.84 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2106287 | 0.83 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL395578 | 0.83 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL333002 | 0.83 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5068019 | 0.82 | TSHR (0.35) | TSHRTHRB | |
| SCHEMBL11319668 | 0.82 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928979-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | Rolic AG (CH) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007033506-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2007-03-29 | — | — | WO | disclosed |