SCHEMBL2493673

SCHEMBL2493673

CN1c2ccc(-c3ccccc3)cc2Sc2cc(-c3ccccc3)ccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.55
NOX1 Q9Y5S8 7/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
MEN1 O00255 1/20 0.54
ADRA2A P08913 1/20 0.54
ADRA2B P18089 1/20 0.54
ADRA2C P18825 1/20 0.54
CHRM3 P20309 1/20 0.54
SLC6A2 P23975 1/20 0.54
HTR2C P28335 1/20 0.54
SLC6A4 P31645 1/20 0.54
DRD3 P35462 1/20 0.54
HTR2B P41595 1/20 0.54
KMT2A Q03164 1/20 0.54
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45
MAPK1 P28482 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
SNCA P37840 4/20 0.42
DRD2 P14416 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16810786 0.95 MAOA (0.66) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL29634104 0.95 MAOA (0.66) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL19649400 0.93 NOX1 (0.49) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL7170967 0.89 MAOA (0.73) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL31067294 0.87 SNCA (0.47) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL16810642 0.86 MAOA (0.57) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL16810782 0.85 MAOA (0.68) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL2501568 0.84 NOX1 (0.50) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL17109671 0.82 MAOA (0.58) MAOANOX1L3MBTL1MEN1ADRA2A
SCHEMBL13846948 0.82 MAOA (0.58) MAOANOX1L3MBTL1MEN1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3935129-B1 LIGANDS FOR NANO-SIZED MATERIALS MERCK PATENT GMBH (DE) 2023-11-29 EP disclosed
US-20230329092-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-10-12 US disclosed
US-20230329092-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-10-12 US disclosed
EP-3645501-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-08-23 EP disclosed
US-20230159434-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-25 US disclosed
US-20230159434-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-25 US disclosed
US-20230046046-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-02-16 US disclosed
EP-3679024-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2022-11-02 EP disclosed
US-11387414-B2 Spirobifluorene compounds for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-07-12 US disclosed
US-20220158101-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2022-05-19 US disclosed
US-20100308714-A1 Phenothiazines, S-Oxides, And S,S-Dioxides As Well As Phenoxazines As Emitters For Oleds BASF AKTIENGESELLSCHAFT (DE) 2010-12-09 US disclosed
US-20100308714-A1 Phenothiazines, S-Oxides, And S,S-Dioxides As Well As Phenoxazines As Emitters For Oleds BASF AKTIENGESELLSCHAFT (DE) 2010-12-09 US disclosed
US-20100308714-A1 Phenothiazines, S-Oxides, And S,S-Dioxides As Well As Phenoxazines As Emitters For Oleds BASF AKTIENGESELLSCHAFT (DE) 2010-12-09 US disclosed
US-20080018238-A1 Use Of Phenothiazine-S-Oxides And Phenothiazine -S,S-Dioxides In The Form Of Matrix Materials For Organic Light-Emitting Diodes BASF AKTIENGESELLSCHAFT (DE) 2008-01-24 US disclosed
US-20080018238-A1 Use Of Phenothiazine-S-Oxides And Phenothiazine -S,S-Dioxides In The Form Of Matrix Materials For Organic Light-Emitting Diodes BASF AKTIENGESELLSCHAFT (DE) 2008-01-24 US disclosed
US-20080018238-A1 Use Of Phenothiazine-S-Oxides And Phenothiazine -S,S-Dioxides In The Form Of Matrix Materials For Organic Light-Emitting Diodes BASF AKTIENGESELLSCHAFT (DE) 2008-01-24 US disclosed
EP-1817806-A1 PHENOTHAZINES, -S-OXIDES, AND S,S-DIOXIDES AS WELL AS PHENOXAZINES AS EMITTERS FOR OLEDS BASF AKTIENGESELLSCHAFT (DE) 2007-08-15 EP disclosed
EP-1817805-A1 USE OF PHENOTHIAZINE-S-OXIDES AND PHENOTHIAZINE -S,S-DIOXIDES IN THE FORM OF MATRIX MATERIALS FOR ORGANIC LIGHT-EMITTING DIODES BASF AKTIENGESELLSCHAFT (DE) 2007-08-15 EP disclosed
WO-2006056416-A1 USE OF PHENOTHIAZINE-S-OXIDES AND PHENOTHIAZINE -S,S-DIOXIDES IN THE FORM OF MATRIX MATERIALS FOR ORGANIC LIGHT-EMITTING DIODES BASF AKTIENGESELLSCHAFT (DE) 2006-06-01 WO disclosed
WO-2006056465-A1 PHENOTHIAZINES, -S-OXIDES, AND S,S-DIOXIDES AS WELL AS PHENOXAZINES AS EMITTERS FOR OLEDS BASF AKTIENGESELLSCHAFT (DE) 2006-06-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230046046-A1 COMPOUNDS FOR ELECTRONIC DEVICES ETV6, CYP2C19, ESR1 MAOA 474/4885NOX1 718/4885L3MBTL1 4196/4885
US-20230329092-A1 MATERIALS FOR ELECTRONIC DEVICES SOD1, GPX1, EFNA1 MAOA 474/4885NOX1 593/4885L3MBTL1 4497/4885
US-11387414-B2 Spirobifluorene compounds for organic electroluminescent devices PKD1, PIEZO1, AQP1 MAOA 2441/4885NOX1 538/4885L3MBTL1 4163/4885
US-20100308714-A1 Phenothiazines, S-Oxides, And S,S-Dioxides As Well As Phenoxazines As Emitters For Oleds PPOX, SMOX, SORD MAOA 82/4885NOX1 458/4885L3MBTL1 2540/4885
US-20220158101-A1 MATERIALS FOR ELECTRONIC DEVICES EED, EPHA6, ERCC1 MAOA 518/4885NOX1 608/4885L3MBTL1 3078/4885
US-20230159434-A1 MATERIALS FOR ELECTRONIC DEVICES OCIAD2, AOC2, OCIAD1 MAOA 17/4885NOX1 1067/4885L3MBTL1 2527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.