Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137828 | 0.89 | MMP1 (0.51) | THRBAKR1B10AKR1B1CACNA1BMEN1 | |
| SCHEMBL891181 | 0.89 | MMP1 (0.51) | THRBAKR1B10AKR1B1CACNA1BMEN1 | |
| Acrylonitrile SCHEMBL27458101 | 0.81 | MMP1 (0.48) | THRBAKR1B10AKR1B1CACNA1BMEN1 | |
| SCHEMBL138625 | 0.80 | THRB (0.55) | THRBAKR1B10AKR1B1MEN1KMT2A | |
| Propene SCHEMBL13387681 | 0.79 | AKR1B10 (0.64) | AKR1B10AKR1B1MEN1KMT2AALDH1A1 | |
| SCHEMBL843436 | 0.78 | AKR1B10 (0.71) | THRBAKR1B10AKR1B1MEN1KMT2A | |
| SCHEMBL3679950 | 0.78 | AKR1B10 (0.71) | AKR1B10AKR1B1MEN1KMT2AALDH1A1 | |
| SCHEMBL843435 | 0.78 | AKR1B10 (0.71) | THRBAKR1B10AKR1B1MEN1KMT2A | |
| SCHEMBL3679949 | 0.78 | AKR1B10 (0.71) | AKR1B10AKR1B1MEN1KMT2AALDH1A1 | |
| SCHEMBL30152200 | 0.77 | THRB (0.56) | THRBAKR1B10AKR1B1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928979-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | Rolic AG (CH) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007033506-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2007-03-29 | — | — | WO | disclosed |