Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | GAPDH | P04406 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 3/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171860 | 0.81 | HPGD (0.59) | HPGDKMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL743447 | 0.81 | MEN1 (0.42) | HPGDKMT2ARAB9AMEN1GAA | |
| SCHEMBL12938972 | 0.81 | KMT2A (0.63) | HPGDKMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL8313887 | 0.81 | CA2 (0.56) | RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL9199661 | 0.79 | CES2 (0.42) | HPGDKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL3369337 | 0.79 | GAA (0.63) | KMT2ARAB9AMEN1SMN1; SMN2GAA | |
| SCHEMBL21664611 | 0.79 | HPGD (0.58) | HPGDKMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL934891 | 0.79 | AOC2 (0.64) | HPGDKMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL6244676 | 0.79 | LMNA (0.59) | KMT2ARAB9AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL3369054 | 0.79 | HTT (0.73) | KMT2ARAB9AMEN1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338768-B1 | Carrier-reporter bead assemblies | NANOMICS BIOSYSTEMS PTY. LTD. (AU) | 2008-03-04 | — | — | US | claimed |
| US-6307018-B1 | TWO OLIGOPEPTIDES ARE LIGATED TO FORM A LIGATION PRODUCT HAVING AN AMINOTHIOESTER LINKAGE; IN A SECOND STEP, THE AMINOTHIOESTER LINKAGE REARRANGES TO FORM A PRODUCT HAVING AN N-SUBSTITUTED AMIDE LINKAGE | THE SCRIPPS RESEARCH INSTITUTE | 2001-10-23 | — | — | US | disclosed |
| WO-1998028434-A1 | GENERAL CHEMICAL LIGATION | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-07-02 | — | — | WO | disclosed |