Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2206586 | 0.85 | HTT (0.62) | HTTSMN1; SMN2ASH1LPRKCIMAPT | |
| SCHEMBL469734 | 0.74 | LMNA (0.55) | HTTSMN1; SMN2CA1CA2MAPT | |
| SCHEMBL6346842 | 0.74 | TPMT (0.55) | TPMTCA1CA2SLC22A2SLC22A1 | |
| SCHEMBL14018619 | 0.74 | HTT (0.58) | HTTSMN1; SMN2ASH1LMAPTPKM | |
| SCHEMBL5068709 | 0.72 | TPMT (0.46) | TPMTCA1CA2SLC22A2SLC22A1 | |
| SCHEMBL999667 | 0.72 | HTT (0.50) | HTTSMN1; SMN2CA1CA2SLC22A2 | |
| SCHEMBL354613 | 0.72 | HTT (0.56) | HTTSMN1; SMN2CA1CA2SLC22A2 | |
| SCHEMBL10503095 | 0.72 | HTT (0.50) | HTTSMN1; SMN2IDO1ASH1LPRKCI | |
| SCHEMBL22130014 | 0.72 | HTT (0.50) | HTTSMN1; SMN2CA1CA2SLC22A2 | |
| SCHEMBL7426560 | 0.72 | LMNA (0.59) | PKMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115219644-A | By means of H 2 Activity evaluation device and method for S-prepared aryl thioamide catalyst | 福州大学 | 2022-10-21 | — | — | CN | disclosed |
| US-10414759-B2 | Phenylthiazoles and uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2019-09-17 | — | — | US | disclosed |
| US-9801861-B2 | Antimicrobial substituted thiazoles and methods of use | PURDUE RESEARCH FOUNDATION (US) | 2017-10-31 | — | — | US | disclosed |
| US-9801861-B2 | Antimicrobial substituted thiazoles and methods of use | PURDUE RESEARCH FOUNDATION (US) | 2017-10-31 | — | — | US | disclosed |
| US-20160243088-A1 | ANTIMICROBIAL SUBSTITUTED THIAZOLES AND METHODS OF USE | PURDUE RESEARCH FOUNDATION (US) | 2016-08-25 | — | — | US | disclosed |
| US-20160243088-A1 | ANTIMICROBIAL SUBSTITUTED THIAZOLES AND METHODS OF USE | PURDUE RESEARCH FOUNDATION (US) | 2016-08-25 | — | — | US | disclosed |
| US-9353072-B2 | Antimicrobial substituted thiazoles and methods of use | PURDUE RESEARCH FOUNDATION (US) | 2016-05-31 | — | — | US | disclosed |
| US-9353072-B2 | Antimicrobial substituted thiazoles and methods of use | PURDUE RESEARCH FOUNDATION (US) | 2016-05-31 | — | — | US | disclosed |
| US-20140121249-A1 | ANTIMICROBIAL SUBSTITUTED THIAZOLES AND METHODS OF USE | PURDUE RESEARCH FOUNDATION | 2014-05-01 | — | — | US | disclosed |
| US-20140121249-A1 | ANTIMICROBIAL SUBSTITUTED THIAZOLES AND METHODS OF USE | PURDUE RESEARCH FOUNDATION | 2014-05-01 | — | — | US | disclosed |
| CN-1220681-C | Indole derivatives as XA factor inhibitors | AVENTIS MEDICINES DEUTSCHLAND (DE) | 2005-09-28 | — | — | CN | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| CN-1283186-A | Indole derivatives as XA factor inhibitors | AWENTIS MEDICINES DEUTSCHLAND (DE) | 2001-02-07 | — | — | CN | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |
| US-5182402-A | 2-Phenylthiazolecarboxylic Acids and Esters | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-01-26 | — | — | US | disclosed |
| US-5084083-A | Phenylthiazolecarboxylic acid derivative herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-28 | — | — | US | disclosed |
| CN-1042907-A | Herbicidal composition | ICI PLC (GB) | 1990-06-13 | — | — | CN | disclosed |
| EP-0368592-A1 | Herbicidal compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10414759-B2 | Phenylthiazoles and uses thereof | TPMT, TST, CLPP | HTT 3052/4885SMN1; SMN2 3041/4885TPMT 1/4885 |
| US-20140121249-A1 | ANTIMICROBIAL SUBSTITUTED THIAZOLES AND METHODS OF USE | CLPP, ELANE, NOD2 | HTT 2691/4885SMN1; SMN2 3558/4885TPMT 395/4885 |
| US-20160243088-A1 | ANTIMICROBIAL SUBSTITUTED THIAZOLES AND METHODS OF USE | CLPP, ELANE, NOD2 | HTT 2691/4885SMN1; SMN2 3558/4885TPMT 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.