Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18644564 | 0.85 | NOS3 (0.39) | CA1CA2PRSS1PRSS2PRSS3 | |
| SCHEMBL10899035 | 0.77 | TPMT (0.50) | TPMTCA1CA2GSK3BSLC22A2 | |
| SCHEMBL13101513 | 0.74 | LMNA (0.55) | CA1CA2 | |
| SCHEMBL2183090 | 0.74 | ALDH1A1 (0.50) | GSK3B | |
| SCHEMBL23950579 | 0.72 | GRIK2 (0.33) | PRSS1PRSS2PRSS3NOS3NOS1 | |
| SCHEMBL17187843 | 0.72 | TPMT (0.59) | TPMTCA1CA2GSK3BNOS3 | |
| SCHEMBL18480045 | 0.72 | PLAU (0.59) | PRSS1PRSS3NOS3NOS1NOS2 | |
| SCHEMBL5068709 | 0.72 | TPMT (0.46) | TPMTCA1CA2GSK3BSLC22A2 | |
| SCHEMBL16705243 | 0.72 | MAPT (0.54) | NOS3NOS1 | |
| SCHEMBL457196 | 0.72 | TPMT (0.59) | TPMTCA1CA2GSK3BNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063213-A2 | PEPTIDES WHICH TARGET TUMOR AND ENDOTHELIAL CELLS, COMPOSITIONS AND USES THEREOF | ATTENUON, LLC (US) | 2004-07-29 | — | — | WO | disclosed |