Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.41 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810604 | 0.91 | MAPT (0.50) | MAPTGAAHTTABCC9ABCC8 | |
| SCHEMBL811427 | 0.82 | HTT (0.48) | MAPTGAAHTTABCC9ABCC8 | |
| SCHEMBL13234660 | 0.80 | PPARA (0.59) | PPARASMN1; SMN2 | |
| SCHEMBL5067776 | 0.79 | PDE7A (0.53) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13305747 | 0.79 | MAPT (0.47) | MAPTGAAHTTABCC9ABCC8 | |
| SCHEMBL811265 | 0.78 | L3MBTL1 (0.48) | MAPTGAAPKML3MBTL1MEN1 | |
| SCHEMBL1478058 | 0.77 | ALDH1A1 (0.53) | MAPTGAAHTTABCC9ABCC8 | |
| SCHEMBL1454638 | 0.77 | MAPT (0.52) | MAPTGAAHTTL3MBTL1MEN1 | |
| SCHEMBL810853 | 0.76 | RAB9A (0.51) | MAPTMEN1KMT2ASMN1; SMN2SIRT2 | |
| SCHEMBL15912553 | 0.76 | ALDH1A1 (0.52) | MAPTGAAHTTABCC9ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971611-A1 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007081517-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-19 | — | — | WO | disclosed |