Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5069096 | 0.87 | OPRM1 (0.31) | OPRM1OPRD1 | |
| SCHEMBL4096451 | 0.86 | KEAP1 (0.41) | OPRM1OPRD1OPRK1 | |
| SCHEMBL2367102 | 0.80 | KEAP1 (0.50) | OPRM1OPRD1OPRK1 | |
| SCHEMBL2367170 | 0.80 | KEAP1 (0.40) | — | |
| SCHEMBL4094024 | 0.79 | MME (0.40) | OPRM1OPRD1OPRK1SCN9A | |
| SCHEMBL3046711 | 0.78 | RXFP1 (0.40) | — | |
| SCHEMBL5070815 | 0.75 | OPRD1 (0.32) | OPRD1 | |
| SCHEMBL5072589 | 0.75 | OPRM1 (0.36) | OPRM1OPRD1OPRK1 | |
| SCHEMBL4088608 | 0.75 | PSEN1 (0.42) | — | |
| SCHEMBL4082724 | 0.74 | OPRM1 (0.33) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007794-A1 | LYSOBACTIN AMIDES | AiCuris GmbH & Co. KG (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118691-A1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO. KG (DE) | 2007-10-25 | — | — | WO | disclosed |