Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.56 |
| ▸ | CASR | P41180 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053008 | 0.89 | MTNR1A (0.51) | MTNR1AMTNR1BL3MBTL1AOC3CASR | |
| SCHEMBL5065146 | 0.86 | AOC3 (0.67) | MTNR1AMTNR1BL3MBTL1AOC3CHRM2 | |
| SCHEMBL13997818 | 0.83 | MTNR1A (0.53) | MTNR1AMTNR1BL3MBTL1AOC3CASR | |
| SCHEMBL19407140 | 0.82 | AOC3 (0.61) | MTNR1AMTNR1BL3MBTL1AOC3CHRM2 | |
| SCHEMBL4596067 | 0.82 | MTNR1A (0.52) | MTNR1AMTNR1BL3MBTL1AOC3CASR | |
| SCHEMBL16149869 | 0.82 | KMT2A (0.55) | MEN1KMT2A | |
| SCHEMBL11436414 | 0.81 | L3MBTL1 (0.62) | MTNR1AMTNR1BL3MBTL1AOC3CASR | |
| SCHEMBL11436413 | 0.81 | L3MBTL1 (0.62) | MTNR1AMTNR1BL3MBTL1AOC3CASR | |
| SCHEMBL11436469 | 0.81 | L3MBTL1 (0.62) | MTNR1AMTNR1BL3MBTL1AOC3CASR | |
| SCHEMBL3584798 | 0.80 | L3MBTL1 (0.61) | MTNR1AMTNR1BL3MBTL1AOC3CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318947-A1 | Inhibitors of Akt Activity | HEERDING DIRK A | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318947-A1 | Inhibitors of Akt Activity | PI4KB, PIK3CA, AKT2 | MTNR1A 4039/4885MTNR1B 3427/4885L3MBTL1 1699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.