SCHEMBL5069405

SCHEMBL5069405

Cc1cc2c(cc1-c1ccccc1)N(C)c1ccccc1N2C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.46
ALDH1A1 P00352 2/20 0.40
TSHR P16473 1/20 0.40
CYP2A6 P11509 1/20 0.39
CYP2B6 P20813 1/20 0.39
DHFR P00374 1/20 0.39
AKT1 P31749 1/20 0.39
BRD4 O60885 2/20 0.38
MAOA P21397 1/20 0.38
BACE1 P56817 1/20 0.37
HTR7 P34969 1/20 0.36
MGLL Q99685 1/20 0.36
HSD17B10 Q99714 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
CCKBR P32239 1/20 0.36
GABRA3 P34903 1/20 0.36
GABRA2 P47869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5069383 0.87 MAOA (0.43) ESR2ALDH1A1AKT1BRD4MAOA
SCHEMBL7169494 0.83 MAOA (0.46) ALDH1A1TSHRAKT1BRD4MAOA
SCHEMBL7263176 0.78 PSMB5 (0.42) ESR2ALDH1A1BACE1KMT2A
SCHEMBL4830408 0.78 ESR2 (0.60) ESR2ALDH1A1TSHRCYP2A6CYP2B6
SCHEMBL5547251 0.75 ESR2 (0.58) ESR2ALDH1A1TSHRCYP2A6CYP2B6
SCHEMBL25643206 0.74 HSD17B10 (0.42) ESR2ALDH1A1TSHRCYP2A6CYP2B6
SCHEMBL21627214 0.73 PGR (0.37) ESR2BRD4BACE1KMT2A
SCHEMBL5069422 0.72 MAOA (0.41) ESR2ALDH1A1AKT1BRD4MAOA
SCHEMBL13636983 0.72
SCHEMBL4571020 0.72 MAOA (0.60) ALDH1A1MAOAHTR7KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7450293-B2 Electrochromic salts, solutions, and devices LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-11-11 US claimed
US-7436570-B2 Electrochromic salts, solutions, and devices LOS ALAMOS NATIONAL SECURITY, LLC (US) 2008-10-14 US claimed
EP-1457813-B1 An improved electrochromic medium capable of producing a pre-selected color GENTEX CORP (US) 2007-01-24 EP claimed
US-20050151467-A1 Electrochromic salts, solutions, and devices TRIAD NATIONAL SECURITY, LLC 2005-07-14 US claimed
US-20050116627-A1 Electrochromic salts, solutions, and devices TRIAD NATIONAL SECURITY, LLC 2005-06-02 US claimed
EP-1457813-A2 An improved electrochromic medium capable of producing a pre-selected color Gentex Corporation (US) 2004-09-15 EP claimed
EP-0972227-B1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORP (US) 2004-07-14 EP claimed
WO-2004000800-A2 ELECTROCHROMIC SALTS, SOLUTIONS, AND DEVICES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-12-31 WO claimed
US-20030234379-A1 Electrochromic salts, solutions, and devices LOS ALAMOS NATIONAL SECURITY, LLC 2003-12-25 US claimed
US-6020987-A Electrochromic medium capable of producing a pre-selected color GENTEX CORPORATION (US) 2000-02-01 US claimed
US-5998617-A MIXTURE OF ELECTROACTIVE MATERIALS AT PRESELECTIVE CONCENTRATION; GRAY COLOR GENTEX CORPORATION (US) 1999-12-07 US claimed
EP-3221420-B1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS SWITCH MAT INC (CA) 2021-02-17 EP disclosed
US-10647913-B2 Photochromic-electrochromic compositions SWITCH MATERIALS INC. (CA) 2020-05-12 US disclosed
US-20170355901-A1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS SOLUTIA CANADA INC. (CA) 2017-12-14 US disclosed
EP-3221420-A1 PHOTOCHROMIC-ELECTROCHROMIC COMPOSITIONS Switch Materials, Inc. (CA) 2017-09-27 EP disclosed
US-6037471-A FOR ELECTROCHROMIC MIRRORS FOR MOTOR VEHICLES GENTEX CORPORATION (US) 2000-03-14 US disclosed
US-6020987-A Electrochromic medium capable of producing a pre-selected color GENTEX CORPORATION (US) 2000-02-01 US disclosed
EP-0972227-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 2000-01-19 EP disclosed
US-5998617-A MIXTURE OF ELECTROACTIVE MATERIALS AT PRESELECTIVE CONCENTRATION; GRAY COLOR GENTEX CORPORATION (US) 1999-12-07 US disclosed
WO-1998044384-A1 AN IMPROVED ELECTROCHROMIC MEDIUM CAPABLE OF PRODUCING A PRE-SELECTED COLOR GENTEX CORPORATION (US) 1998-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050151467-A1 Electrochromic salts, solutions, and devices F8, ETV6, HCN4 ESR2 769/4885ALDH1A1 4195/4885TSHR 3335/4885
US-20050116627-A1 Electrochromic salts, solutions, and devices F8, ETV6, HCN4 ESR2 769/4885ALDH1A1 4195/4885TSHR 3335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.