SCHEMBL7263176

SCHEMBL7263176

Cc1ccc2c(c1)N(C)c1cc(-c3ccccc3)c(-c3ccccc3)cc1N2C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 1/20 0.42
HDAC7 Q8WUI4 1/20 0.40
MAOB P27338 2/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.38
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MAPT P10636 4/20 0.38
LMNA P02545 3/20 0.38
TP53 P04637 1/20 0.38
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
RECQL P46063 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TERT O14746 1/20 0.37
HPRT1 P00492 1/20 0.37
ESR2 Q92731 1/20 0.36
BACE1 P56817 1/20 0.35
CHEK1 O14757 1/20 0.35
AURKA O14965 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5069383 0.86 MAOA (0.43) ALDH1A1NPSR1ESR2BACE1
SCHEMBL12901940 0.86 MAOA (0.43) L3MBTL1MAPTLMNAKMT2AMEN1
SCHEMBL17339860 0.83 TERT (0.41) ALDH1A1KDM4EMAPTLMNATP53
SCHEMBL4624622 0.83 TERT (0.41) ALDH1A1KDM4EMAPTLMNATP53
SCHEMBL5069405 0.78 ESR2 (0.46) ALDH1A1KMT2AESR2BACE1
SCHEMBL12841526 0.78 OPRK1 (0.40) ALDH1A1KDM4EL3MBTL1LMNATP53
SCHEMBL19532247 0.75 FFAR4 (0.43) ALDH1A1L3MBTL1MAPTLMNATP53
SCHEMBL3005820 0.74 ELANE (0.52) PSMB5HDAC7MAOBPTGDR2ALDH1A1
SCHEMBL10072419 0.74 OPRK1 (0.43) ALDH1A1KDM4EL3MBTL1LMNATP53
SCHEMBL25137384 0.73 HTT (0.42) ALDH1A1KDM4EMAPTLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6661559-B2 Transparent substrate having an electrically conductive material; redox electroactive compounds; colorimetric analysis GENTEX CORPORATION 2003-12-09 US disclosed
US-20020051278-A1 Electrochromic media for producing a preselected color and devices comprising same BYKER HARLAN J (US) 2002-05-02 US disclosed
US-6288825-B1 Electrochromic media for producing a preselected color and devices comprising same GENTEX CORPORATION 2001-09-11 US disclosed
US-6141137-A Electrochromic media for producing a preselected color GENTEX CORPORATION (US) 2000-10-31 US disclosed