SCHEMBL5070359

SCHEMBL5070359

O=C(O)CC(=O)OCCCOC(=O)CC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.42
SRR Q9GZT4 1/20 0.42
FAAH O00519 2/20 0.41
NAAA Q02083 1/20 0.39
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 3/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
DGKA P23743 1/20 0.34
ALDH1A1 P00352 1/20 0.33
RAD52 P43351 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
POLB P06746 1/20 0.33
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7753303 0.94 FAAH (0.45) LDHASRRFAAHNAAAMGAM
SCHEMBL31040363 0.92 FAAH (0.48) LDHASRRFAAHNAAATSHR
SCHEMBL6681551 0.87 CAMK2A (0.40) LDHASRRFAAHNAAAMGAM
SCHEMBL5393914 0.87 TSHR (0.48) FAAHTSHRKMT2AALDH1A1NPSR1
SCHEMBL6064969 0.85 FAAH (0.36) LDHASRRFAAHNAAAMGAM
SCHEMBL28203404 0.85 ACHE (0.43) LDHASRRFAAHNAAAGAA
SCHEMBL217404 0.85 ALDH1A1 (0.54) FAAHNAAATSHRDGKAALDH1A1
SCHEMBL29267684 0.85 FAAH (0.44) LDHASRRFAAHNAAAMGAM
SCHEMBL31416868 0.85 THRB (0.42) LDHASRRFAAHNAAAMGAM
SCHEMBL10910388 0.84 ACHE (0.46) FAAHNAAAGAATSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12023783-B2 Abrasive articles including a blend of abrasive particles and method of forming and using the same SAINT-GOBAIN ABRASIVES, INC. (US) 2024-07-02 US disclosed
CN-114929833-A High-thermal-conductivity layered phase-change composite material 罗杰斯公司 2022-08-19 CN disclosed
US-20220161392-A1 ABRASIVE ARTICLES INCLUDING A BLEND OF ABRASIVE PARTICLES AND METHOD OF FORMING AND USING THE SAME SAINT GOBAIN ABRASIVES INC (US) 2022-05-26 US disclosed
US-11260504-B2 Abrasive articles including a blend of abrasive particles and method of forming and using the same SAINT-GOBAIN ABRASIVES, INC. (US) 2022-03-01 US disclosed
EP-2693983-B1 EAR SCAFFOLD NORTHWOOD MEDICAL INNOVATION LTD (GB) 2017-06-28 EP disclosed
EP-1940320-A1 SURGICAL SCAFFOLD WEST HERTFORDSHIRE HOSPITALS NHS TRUST (GB) 2008-07-09 EP disclosed
WO-2007023296-A1 SURGICAL SCAFFOLD WEST HERTFORDSHIRE HOSPITALS NHS TRUST (GB) 2007-03-01 WO disclosed
EP-0662006-B1 Polymer compositions and device for OCCLUSION OF CHANNELS IN LIVING MAMMALS LANDEC CORP (US) 1999-11-24 EP disclosed
EP-0662006-A1 OCCLUSION OF CHANNELS IN LIVING MAMMALS LANDEC CORPORATION (US) 1995-07-12 EP disclosed
WO-1994005342-A1 OCCLUSION OF CHANNELS IN LIVING MAMMALS LANDEC CORPORATION (US) 1994-03-17 WO disclosed