Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5070663 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRPOLBMAPTSLC5A1 | |
| SCHEMBL5135464 | 0.98 | ALDH1A1 (0.40) | ALDH1A1TSHRPOLBMAPTSLC5A1 | |
| SCHEMBL5663675 | 0.92 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPTHTR1ADRD2 | |
| SCHEMBL5662980 | 0.92 | MAOA (0.36) | ALDH1A1TSHRPOLBMAPTHTR1A | |
| SCHEMBL5664288 | 0.88 | ALDH1A1 (0.48) | ALDH1A1TSHRPOLBMAPTSLC5A1 | |
| SCHEMBL5073359 | 0.86 | MAPT (0.45) | ALDH1A1MAPTHTR1ADRD2MAOA | |
| SCHEMBL5662273 | 0.85 | TP53 (0.37) | ALDH1A1TSHRMAPTHTR1ADRD2 | |
| SCHEMBL29377653 | 0.84 | ALDH1A1 (0.48) | ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL595200 | 0.84 | ALDH1A1 (0.48) | ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL28682859 | 0.83 | SLC5A1 (0.43) | ALDH1A1TSHRPOLBSLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966290-A2 | POROUS MONOLITHIC ORGANIC COPOLYMER FOR BIOPOLYMER CHROMATOGRAPHY | Leopold-Franzens-Universität Innsbruck (AT) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007073865-A2 | POROUS MONOLITHIC ORGANIC COPOLYMER FOR BIOPOLYMER CHROMATOGRAPHY | LEOPOLD-FRANZENS-UNIVERSITÄT INNSBRUCK (AT) | 2007-07-05 | — | — | WO | disclosed |
| US-20070144972-A1 | Monolithic Organic Copolymer for Biopolymer Chromatography | LEOPOLD-FRANZENS-UNIVERSITAT INNSBRUCK (AT) | 2007-06-28 | — | — | US | disclosed |