Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5135464 | 0.91 | ALDH1A1 (0.40) | ALDH1A1TSHRMAPTHTR1ADRD2 | |
| SCHEMBL5070663 | 0.88 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPTHTR1ADRD2 | |
| SCHEMBL5070664 | 0.88 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPTHTR1ADRD2 | |
| SCHEMBL5662401 | 0.88 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPTHTR1ADRD2 | |
| SCHEMBL9806380 | 0.86 | ALDH1A1 (0.59) | ALDH1A1TSHRMAOAMAOBPOLB | |
| SCHEMBL50012 | 0.86 | ALDH1A1 (0.65) | ALDH1A1TSHRMAPTMAOAMAOB | |
| SCHEMBL1647493 | 0.86 | ALDH1A1 (0.65) | ALDH1A1TSHRMAPTMAOAMAOB | |
| SCHEMBL5662980 | 0.81 | MAOA (0.36) | ALDH1A1TSHRMAPTHTR1ADRD2 | |
| SCHEMBL5141146 | 0.81 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPTHTR1ADRD2 | |
| SCHEMBL1646806 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TSHRMAOAMAOBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070144972-A1 | Monolithic Organic Copolymer for Biopolymer Chromatography | LEOPOLD-FRANZENS-UNIVERSITAT INNSBRUCK (AT) | 2007-06-28 | — | — | US | disclosed |