Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5070663 | 0.92 | ALDH1A1 (0.41) | MAOAMAOBALDH1A1TSHRMAPT | |
| SCHEMBL5070664 | 0.92 | ALDH1A1 (0.41) | MAOAMAOBALDH1A1TSHRMAPT | |
| SCHEMBL5662273 | 0.91 | TP53 (0.37) | MAOAMAOBALDH1A1TSHRCYP19A1 | |
| SCHEMBL5135464 | 0.90 | ALDH1A1 (0.40) | MAOAMAOBALDH1A1TSHRMAPT | |
| SCHEMBL5664311 | 0.90 | MAOA (0.38) | MAOAMAOBALDH1A1CYP19A1MAPT | |
| SCHEMBL5070696 | 0.89 | TP53 (0.38) | MAOAMAOBALDH1A1TSHRMAPT | |
| SCHEMBL5073377 | 0.87 | TP53 (0.39) | MAOAMAOBALDH1A1TSHRMAPT | |
| SCHEMBL5070677 | 0.86 | TP53 (0.38) | MAOAMAOBALDH1A1TSHRMAPT | |
| SCHEMBL5663675 | 0.85 | ALDH1A1 (0.41) | MAOAMAOBALDH1A1TSHRMAPT | |
| SCHEMBL1646806 | 0.85 | ALDH1A1 (0.48) | MAOAMAOBALDH1A1TSHRCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070144972-A1 | Monolithic Organic Copolymer for Biopolymer Chromatography | LEOPOLD-FRANZENS-UNIVERSITAT INNSBRUCK (AT) | 2007-06-28 | — | — | US | disclosed |