Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5073377 | 0.98 | TP53 (0.39) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL5070696 | 0.97 | TP53 (0.38) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL5662273 | 0.95 | TP53 (0.37) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL5665065 | 0.92 | TP53 (0.44) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL5664311 | 0.88 | MAOA (0.38) | ALDH1A1MAOAMAOBABCB1HTR1A | |
| SCHEMBL5662980 | 0.86 | MAOA (0.36) | ALDH1A1TSHRMAOAMAOBABCB1 | |
| SCHEMBL5662401 | 0.85 | ALDH1A1 (0.42) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL15809482 | 0.83 | TP53 (0.40) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL595016 | 0.82 | TP53 (0.52) | TP53TDP1ALDH1A1TSHRFAAH | |
| SCHEMBL29375309 | 0.82 | TP53 (0.52) | TP53TDP1ALDH1A1TSHRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966290-A2 | POROUS MONOLITHIC ORGANIC COPOLYMER FOR BIOPOLYMER CHROMATOGRAPHY | Leopold-Franzens-Universität Innsbruck (AT) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007073865-A2 | POROUS MONOLITHIC ORGANIC COPOLYMER FOR BIOPOLYMER CHROMATOGRAPHY | LEOPOLD-FRANZENS-UNIVERSITÄT INNSBRUCK (AT) | 2007-07-05 | — | — | WO | disclosed |
| US-20070144972-A1 | Monolithic Organic Copolymer for Biopolymer Chromatography | LEOPOLD-FRANZENS-UNIVERSITAT INNSBRUCK (AT) | 2007-06-28 | — | — | US | disclosed |