SCHEMBL5071007

SCHEMBL5071007

c1ccc(CC(Cc2ccccc2)=C(Cc2ccccc2)Cc2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.60
CES2 O00748 1/20 0.60
AKR1B1 P15121 1/20 0.60
TSHR P16473 2/20 0.53
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
CALM1 P0DP23 1/20 0.50
FNTA P49354 1/20 0.48
FNTB P49356 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 2/20 0.46
MAPK1 P28482 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CTBP2 P56545 1/20 0.46
EPHX2 P34913 1/20 0.46
IDO1 P14902 2/20 0.46
THRB P10828 1/20 0.46
TP53 P04637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10717034 0.88 CES1 (0.55) CES1CES2AKR1B1TSHRMEN1
SCHEMBL20534688 0.87 CES1 (0.48) CES1CES2AKR1B1TSHRMEN1
SCHEMBL9386470 0.83 CES1 (0.50) CES1CES2AKR1B1TSHRMEN1
SCHEMBL28742090 0.83 AKR1B1 (0.62) CES1CES2AKR1B1TSHRMEN1
SCHEMBL351698 0.80 CES1 (0.60) CES1CES2AKR1B1TSHRMEN1
SCHEMBL4981463 0.80 CES1 (0.60) CES1CES2AKR1B1TSHRMEN1
SCHEMBL22607713 0.79 CES1 (0.58) CES1CES2AKR1B1TSHRMEN1
SCHEMBL11112278 0.77 CES1 (0.44) CES1CES2AKR1B1TSHRMEN1
SCHEMBL11795977 0.77 CES2 (0.44) CES1CES2AKR1B1TSHRMEN1
SCHEMBL9275452 0.77 CES1 (0.44) CES1CES2AKR1B1TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025090486-A1 MAGNET WIRE WITH LOW-PERMITTIVITY INSULATION ESSEX SOLUTIONS USA LLC (US) 2025-05-01 WO disclosed
US-20250079054-A1 MAGNET WIRE WITH LOW-PERMITTIVITY INSULATION BANK OF AMERICA, N.A., AS AGENT 2025-03-06 US disclosed
EP-1214070-A4 POLYHYDROXYLATED BENZENE-CONTAINING COMPOUNDS ARCH DEV CORP (US) 2008-07-16 EP disclosed
US-20030139477-A1 Polyhydroxylated benzene-containing compounds NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-07-24 US disclosed
EP-1214070-A2 POLYHYDROXYLATED BENZENE-CONTAINING COMPOUNDS Arch Development Corporation (US) 2002-06-19 EP disclosed
WO-2001060319-A2 POLYHYDROXYLATED BENZENE-CONTAINING COMPOUNDS ARCH DEVELOPMENT CORPORATION (US) 2001-08-23 WO disclosed
EP-0686685-B1 Photochromic dye RODENSTOCK OPTIK G (DE) 1998-12-02 EP disclosed
EP-0686685-A2 Photochromic dye Optische Werke G. Rodenstock (DE) 1995-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139477-A1 Polyhydroxylated benzene-containing compounds LIPE, PNLIP, SHBG CES1 90/4885CES2 293/4885AKR1B1 434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.