Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788948 | 0.93 | ESR1 (0.61) | ESR1ESR2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL36980 | 0.92 | MEP1B (0.44) | ESR1ESR2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL28439714 | 0.89 | CALM1 (0.52) | IDH1PTPN2PTPN1PTPN6 | |
| SCHEMBL836033 | 0.84 | CYP17A1 (0.56) | ESR1ESR2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL14421388 | 0.82 | ESR1 (0.39) | ESR1ESR2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL5071987 | 0.78 | CYP17A1 (0.59) | ESR1ESR2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL14421368 | 0.76 | PTGS1 (0.45) | ESR1ESR2MEP1BDBHPTGS1 | |
| SCHEMBL30058625 | 0.75 | CA1 (0.61) | ESR1ESR2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL545298 | 0.75 | CA1 (0.61) | ESR1ESR2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL27739780 | 0.75 | PTGS1 (0.66) | ESR1ESR2PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345135-B2 | Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin | MITSUI CHEMICALS, INC. (JP) | 2008-03-18 | — | — | US | disclosed |