Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of Propionic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.67 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PPARD | Q03181 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL6734624 | 0.97 | FFAR3 (0.62) | FFAR3LDHASRRHDAC3HDAC1 | |
| Propionic Acid SCHEMBL4664260 | 0.94 | FFAR3 (0.59) | FFAR3LDHASRRHDAC3HDAC1 | |
| Propionic Acid SCHEMBL28107860 | 0.94 | FFAR3 (0.59) | FFAR3LDHASRRHDAC3HDAC1 | |
| Propionic Acid SCHEMBL2167213 | 0.91 | FFAR3 (0.56) | FFAR3LDHASRRHDAC3HDAC1 | |
| Propionic Acid SCHEMBL2777824 | 0.90 | FFAR3 (0.71) | FFAR3LDHASRRHDAC3HDAC1 | |
| Propionic Acid SCHEMBL28174768 | 0.90 | FFAR3 (0.71) | FFAR3LDHASRRHDAC3HDAC1 | |
| Propionic Acid SCHEMBL28589623 | 0.87 | FFAR3 (0.67) | FFAR3LDHASRRHDAC3HDAC1 | |
| Propionic Acid SCHEMBL28210432 | 0.87 | FFAR3 (0.67) | FFAR3LDHASRRHDAC3HDAC1 | |
| Propionic Acid SCHEMBL28304976 | 0.87 | FFAR3 (0.67) | FFAR3LDHASRRHDAC3HDAC1 | |
| Propionic Acid SCHEMBL28304974 | 0.87 | FFAR3 (0.67) | FFAR3LDHASRRHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043150-A | New crystal form of dabigatran etexilate ethyl ester hydrochloride as well as preparation method and application thereof | 天津睿创康泰生物技术有限公司 | 2023-11-10 | — | — | CN | disclosed |
| WO-2023109204-A1 | SULFONATION METHOD FOR UNSATURATED ALKANE OF ELECTRON-WITHDRAWING GROUP | 青岛科技大学 | 2023-06-22 | — | — | WO | disclosed |
| US-10280181-B2 | Coloring composition, anisotropic light absorption film, laminate, polarizing plate, image display device and compound | FUJIFILM CORPORATION (JP) | 2019-05-07 | — | — | US | disclosed |
| EP-2834224-B1 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND SALTS THEREOF | MSN LAB LTD (IN) | 2018-06-06 | — | — | EP | disclosed |
| US-20160340367-A1 | COLORING COMPOSITION, ANISOTROPIC LIGHT ABSORPTION FILM, LAMINATE, POLARIZING PLATE, IMAGE DISPLAY DEVICE AND COMPOUND | FUJIFILM CORPORATION (JP) | 2016-11-24 | — | — | US | disclosed |
| EP-2834224-A2 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND SALTS THEREOF | MSN Laboratories Limited (IN) | 2015-02-11 | — | — | EP | disclosed |
| WO-2014093252-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF USE | NEXMED HOLDINGS, INC. (US) | 2014-06-19 | — | — | WO | disclosed |
| WO-2014041559-A2 | PROCESS FOR THE PREPARATION OF DABIGATRAN ETEXILATE AND INTERMEDIATES THEREOF | GLENMARK PHARMACEUTICALS LIMITED; GLENMARK GENERICS LIMITED (IN) | 2014-03-20 | — | — | WO | disclosed |
| WO-2013150545-A2 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND SALTS THEREOF | MSN LABORATORIES LIMITED (IN) | 2013-10-10 | — | — | WO | disclosed |
| CN-101395131-B | Method for producing aminoacetylpyrrolidinecarbonitrile derivative and production intermediate thereof | KYORIN SEIYAKU KK | 2012-11-14 | — | — | CN | disclosed |
| CN-101395131-A | Method for producing aminoacetylpyrrolidinecarbonitrile derivative and production intermediate thereof | KYORIN SEIYAKU KK (JP) | 2009-03-25 | — | — | CN | disclosed |
| EP-1991552-A2 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | Epoch Biosciences, Inc. (US) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007098182-A2 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES, INC. (US) | 2007-08-30 | — | — | WO | disclosed |
| CN-1214026-C | Indol-3-yl derivatives | MERCK PATENT GMBH (DE) | 2005-08-10 | — | — | CN | disclosed |
| US-20050095293-A1 | Administration form for the oral application of poorly soluble drugs | BOEHRINGER INGELHEIM PHARMA GMBH CO. KG (DE) | 2005-05-05 | — | — | US | disclosed |
| CN-1398264-A | Indol-3-yl derivatives | MERCK PATENT GMBH (DE) | 2003-02-19 | — | — | CN | disclosed |
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4336200-A | 17α-Acyloxy-5β-corticoids | THE UPJOHN COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160340367-A1 | COLORING COMPOSITION, ANISOTROPIC LIGHT ABSORPTION FILM, LAMINATE, POLARIZING PLATE, IMAGE DISPLAY DEVICE AND COMPOUND | AHR, CTNNA1, HTR1D | FFAR3 1656/4885LDHA 2074/4885SRR 1307/4885 |
| US-10280181-B2 | Coloring composition, anisotropic light absorption film, laminate, polarizing plate, image display device and compound | AHR, CTNNA1, HTR1D | FFAR3 1656/4885LDHA 2074/4885SRR 1307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.