Bronopol

Bronopol

SCHEMBL5073725

N#CSCSC#N.O=[N+]([O-])C(Br)(CO)CO.O=[N+]([O-])C(CO)(CO)CO

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.55
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bronopol SCHEMBL5076392 0.82 LMNA (0.81) LMNA
Bronopol SCHEMBL23260 0.74
Bronopol SCHEMBL7069554 0.74 LMNA (1.00) LMNAALDH1A1TSHRTDP1
Bronopol SCHEMBL31490721 0.72 LMNA (0.94) LMNAALDH1A1TSHRTDP1
SCHEMBL22312 0.70 LMNA (0.52) LMNAALDH1A1TSHRTDP1
SCHEMBL28652710 0.70 LMNA (0.52) LMNAALDH1A1TSHRTDP1
Bronopol SCHEMBL1702852 0.68 LMNA (0.85) LMNAALDH1A1TSHRTDP1
Methane SCHEMBL1141018 0.67 LMNA (0.50) LMNAALDH1A1TSHRTDP1
Potassium SCHEMBL8328705 0.67 LMNA (0.50) LMNAALDH1A1TSHRTDP1
Ammonia Solution, Strong SCHEMBL27791838 0.67 LMNA (0.50) LMNAALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008138817-A2 METHOD AND COMPOSITION FOR DISINFECTING DELICATE SURFACES BASF SE (DE) 2008-11-20 WO disclosed