Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11223470 | 1.00 | DNM1 (0.43) | DNM1MEN1KMT2ACES2CES1 | |
| SCHEMBL9245737 | 1.00 | DNM1 (0.43) | DNM1MEN1KMT2ACES2CES1 | |
| SCHEMBL17104769 | 0.92 | TP53 (0.39) | DNM1MEN1KMT2ACES2CES1 | |
| SCHEMBL5320699 | 0.84 | TP53 (0.42) | DNM1CES2CES1TP53SMN1; SMN2 | |
| SCHEMBL12040726 | 0.84 | KCNH2 (0.47) | DNM1MEN1KMT2AEPHX2TP53 | |
| SCHEMBL9244232 | 0.84 | KCNH2 (0.47) | DNM1MEN1KMT2AEPHX2TP53 | |
| SCHEMBL9247311 | 0.84 | KCNH2 (0.56) | TP53KCNH2SIGMAR1CETP | |
| SCHEMBL5690887 | 0.82 | THRA (0.35) | TP53SMN1; SMN2KCNH2 | |
| SCHEMBL8019206 | 0.82 | ESR1 (0.38) | CES2CES1TP53SMN1; SMN2 | |
| SCHEMBL5366304 | 0.81 | SIGMAR1 (0.41) | DNM1MEN1KMT2ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697465-B1 | POLYMER NANOCOMPOSITES AND METHODS FOR THEIR PREPARATION | GEN ELECTRIC (US) | 2008-02-13 | — | — | EP | disclosed |
| US-20050137310-A1 | Polymer nanocomposites and methods for their preparation | CITIBANK, N.A., AS COLLATERAL AGENT | 2005-06-23 | — | — | US | disclosed |