Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12040726 | 1.00 | KCNH2 (0.47) | KCNH2SIGMAR1CETPDNM1HTR2A | |
| SCHEMBL9247311 | 0.93 | KCNH2 (0.56) | KCNH2SIGMAR1CETPHTR2ATP53 | |
| SCHEMBL12040713 | 0.86 | SIGMAR1 (0.49) | KCNH2SIGMAR1HTR2AOPRM1DRD3 | |
| SCHEMBL9245737 | 0.84 | DNM1 (0.43) | KCNH2SIGMAR1CETPDNM1MEN1 | |
| SCHEMBL11223470 | 0.84 | DNM1 (0.43) | KCNH2SIGMAR1CETPDNM1MEN1 | |
| SCHEMBL5074191 | 0.84 | DNM1 (0.43) | KCNH2SIGMAR1CETPDNM1MEN1 | |
| SCHEMBL349504 | 0.82 | ALDH1A1 (0.48) | SIGMAR1HTR2ASMN1; SMN2HPGD | |
| SCHEMBL779931 | 0.81 | MAOA (0.52) | SIGMAR1HTR2A | |
| SCHEMBL12040649 | 0.80 | SIGMAR1 (0.47) | KCNH2SIGMAR1OPRM1DRD3 | |
| SCHEMBL19063505 | 0.79 | TP53 (0.42) | KCNH2SIGMAR1HTR2ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401390-A | Oxidation of mercaptans to disulfides | UOP (US) | 1995-03-28 | — | — | US | disclosed |
| US-5318936-A | Metal chelate dispersed on catalyst support; layered double hydroxide; for oxidizing mercaptans to disulfides | UOP (US) | 1994-06-07 | — | — | US | disclosed |
| US-5286372-A | Catalyst is composed of metal chelate dispersed on basic support which is either a solid solution of metal oxides or a layered double hydroxide | UOP (US) | 1994-02-15 | — | — | US | disclosed |
| US-5232887-A | Metal chelate diispersed on a metal oxide or layered double hydroxide support | UOP (US) | 1993-08-03 | — | — | US | disclosed |
| US-4913802-A | OXIDIZING MERCAPTAN TO DISULFIDES USING AMMONIUM HYDROXIDE AND A QUATERNARY AMMONIUM HYDROXIDE WITH CATALYTIC COMPOSITE | UOP (US) | 1990-04-03 | — | — | US | disclosed |