Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.55 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.55 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.55 |
| ▸ | TYMP | P19971 | 1/20 | 0.53 |
| ▸ | HINT1 | P49773 | 3/20 | 0.53 |
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.50 |
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | KRAS | P01116 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3425765 | 0.91 | POLB (0.66) | POLBP2RY2P2RY4P2RY6TYMP | |
| SCHEMBL8506523 | 0.89 | POLB (0.61) | POLBP2RY2P2RY4P2RY6TYMP | |
| SCHEMBL5360855 | 0.87 | POLB (0.62) | POLBP2RY2P2RY4P2RY6TYMP | |
| SCHEMBL9545419 | 0.85 | POLB (0.60) | POLBP2RY2P2RY4P2RY6TYMP | |
| SCHEMBL7915394 | 0.85 | HINT1 (0.71) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL5347882 | 0.85 | POLB (0.63) | POLBP2RY2P2RY4P2RY6TYMP | |
| SCHEMBL8622463 | 0.84 | POLB (0.67) | POLBP2RY2P2RY4P2RY6TYMP | |
| SCHEMBL8622459 | 0.84 | POLB (0.67) | POLBP2RY2P2RY4P2RY6TYMP | |
| SCHEMBL9017499 | 0.84 | POLB (0.55) | POLBP2RY2P2RY4P2RY6TYMP | |
| SCHEMBL15012843 | 0.83 | POLB (0.70) | POLBP2RY2P2RY4P2RY6TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200215092-A1 | Oligonucleotide Analogues Incorporating 5-Aza-Cytosine Therein | ASTEX PHARMACEUTICALS, INC. | 2020-07-09 | — | — | US | disclosed |
| EP-1943264-A2 | OLIGONUCLEOTIDE ANALOGUES INCORPORATING 5-AZA-CYTOSINE THEREIN | SuperGen, Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007041071-A2 | OLIGONUCLEOTIDE ANALOGUES INCORPORATING 5-AZA-CYTOSINE THEREIN | SUPERGEN, INC. (US) | 2007-04-12 | — | — | WO | disclosed |
| EP-0902788-A1 | NUCLEOSIDE DERIVATIVES, AND THEIR USE IN OLIGONUCLEOTIDE SYNTHESIS | CIS BIO INTERNATIONAL (FR) | 1999-03-24 | — | — | EP | disclosed |
| WO-1997042207-A1 | NUCLEOSIDE DERIVATIVES, AND THEIR USE IN OLIGONUCLEOTIDE SYNTHESIS | CIS BIO INTERNATIONAL (FR) | 1997-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200215092-A1 | Oligonucleotide Analogues Incorporating 5-Aza-Cytosine Therein | DCTD, DNMT3B, NT5C3B | POLB 52/4885P2RY2 1688/4885P2RY4 925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.