Sugi Predict

Sugi Predict / Compounds / SCHEMBL7915394

SCHEMBL7915394

SCHEMBL7915394

Nc1nc2c(ncn2[C@@H]2O[C@H](COC(=O)COc3ccccc3)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.71

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ HINT1 P49773 10/20 0.71
▸ GSK3A P49840 2/20 0.69
▸ RPS6KA3 P51812 2/20 0.69
▸ MAPK14 Q16539 2/20 0.69
▸ PNP P00491 1/20 0.64
▸ NT5E P21589 1/20 0.61
▸ KRAS P01116 4/20 0.59
▸ TGM2 P21980 1/20 0.57
▸ TAAR1 Q96RJ0 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439016 0.89 HINT1 (0.78) HINT1GSK3ARPS6KA3MAPK14PNP
SCHEMBL5219707 0.87 GSK3A (0.80) HINT1GSK3ARPS6KA3MAPK14PNP
SCHEMBL9295418 0.87 HINT1 (0.75) HINT1GSK3ARPS6KA3MAPK14PNP
SCHEMBL9295421 0.87 HINT1 (0.75) HINT1GSK3ARPS6KA3MAPK14PNP
SCHEMBL2994004 0.86 HINT1 (0.72) HINT1GSK3ARPS6KA3MAPK14PNP
SCHEMBL5075569 0.85 POLB (0.60) HINT1GSK3ARPS6KA3MAPK14PNP
SCHEMBL784432 0.85 HINT1 (0.75) HINT1GSK3ARPS6KA3MAPK14PNP
SCHEMBL5358571 0.84 HINT1 (0.70) HINT1GSK3ARPS6KA3MAPK14PNP
SCHEMBL6065959 0.84 HINT1 (0.77) HINT1GSK3ARPS6KA3MAPK14PNP
SCHEMBL2108262 0.84 HINT1 (0.53) HINT1GSK3ARPS6KA3MAPK14PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400168-A2 ANTISENSE NUCLEIC ACIDS Nippon Shinyaku Co., Ltd. (JP) 2024-07-17 — — EP disclosed
CN-118207212-A Antisense nucleic acid 日本新药株式会社 2024-06-18 — — CN disclosed
US-20230151050-A1 ANTISENSE NUCLEIC ACIDS NIPPON SHINYAKU CO., LTD. (JP) 2023-05-18 — — US disclosed
US-20210340171-A1 ANTISENSE NUCLEIC ACIDS NIPPON SHINYAKU CO., LTD. (JP) 2021-11-04 — — US disclosed
US-20210284680-A1 ANTISENSE NUCLEIC ACIDS NIPPON SHINYAKU CO., LTD. (JP) 2021-09-16 — — US disclosed
US-20210222169-A1 ANTISENSE NUCLEIC ACIDS NIPPON SHINYAKU CO., LTD. (JP) 2021-07-22 — — US disclosed
US-20210198306-A1 ANTISENSE NUCLEIC ACIDS NIPPON SHINYAKU CO., LTD. (JP) 2021-07-01 — — US disclosed
US-20210179659-A1 ANTISENSE NUCLEIC ACIDS NIPPON SHINYAKU CO., LTD. (JP) 2021-06-17 — — US disclosed
US-11028122-B1 Antisense nucleic acids NIPPON SHINYAKU CO., LTD. (JP) 2021-06-08 — — US disclosed
US-10870676-B2 Antisense nucleic acids NIPPON SHINYAKU CO., LTD. (JP) 2020-12-22 — — US disclosed
US-20150166995-A1 ANTISENSE NUCLEIC ACIDS NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY (JP) 2015-06-18 — — US disclosed
US-8969551-B2 Morpholino nucleic acid derivatives NIPPON SHINYAKU CO., LTD. (JP) 2015-03-03 — — US disclosed
US-20140343266-A1 ANTISENSE NUCLEIC ACIDS NIPPON SHINYAKU CO., LTD. (JP) 2014-11-20 — — US disclosed
EP-2799548-A1 ANTISENSE NUCLEIC ACID Nippon Shinyaku Co., Ltd. (JP) 2014-11-05 — — EP disclosed
US-20130211062-A1 ANTISENSE NUCLEIC ACIDS NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY (JP) 2013-08-15 — — US disclosed
EP-2623507-A1 MORPHOLINO NUCLEIC ACID DERIVATIVE Nippon Shinyaku Co., Ltd. (JP) 2013-08-07 — — EP disclosed
US-20130197220-A1 Morpholino Nucleic Acid Derivatives NIPPON SHINYAKU CO., LTD. (JP) 2013-08-01 — — US disclosed
EP-2612917-A1 ANTISENSE NUCLEIC ACID Nippon Shinyaku Co., Ltd. (JP) 2013-07-10 — — EP disclosed
EP-1159064-A1 METHOD FOR PHOTOLYTICALLY DEPROTECTING IMMOBILIZED NUCLEOSIDE DERIVATIVES, ESPECIALLY IN THE PRODUCTION OF DNA CHIPS NIGU CHEMIE GMBH (DE) 2001-12-05 — — EP disclosed
WO-2000053309-A1 METHOD FOR PHOTOLYTICALLY DEPROTECTING IMMOBILIZED NUCLEOSIDE DERIVATIVES, ESPECIALLY IN THE PRODUCTION OF DNA CHIPS NIGU CHEMIE GMBH (DE) 2000-09-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11028122-B1 Antisense nucleic acids UTRN, RBM17, UPF1 HINT1 3077/4885GSK3A 3983/4885RPS6KA3 3002/4885
US-20210198306-A1 ANTISENSE NUCLEIC ACIDS UTRN, RBM17, UPF1 HINT1 3077/4885GSK3A 3983/4885RPS6KA3 3002/4885
US-20130197220-A1 Morpholino Nucleic Acid Derivatives MORF4L1, METTL16, METTL3 HINT1 2485/4885GSK3A 3601/4885RPS6KA3 2851/4885
US-20210284680-A1 ANTISENSE NUCLEIC ACIDS UTRN, RBM17, UPF1 HINT1 3077/4885GSK3A 3983/4885RPS6KA3 3002/4885
US-20210340171-A1 ANTISENSE NUCLEIC ACIDS UTRN, RBM17, UPF1 HINT1 3077/4885GSK3A 3983/4885RPS6KA3 3002/4885
US-20230151050-A1 ANTISENSE NUCLEIC ACIDS UTRN, RBM17, UPF1 HINT1 3077/4885GSK3A 3983/4885RPS6KA3 3002/4885
US-20130211062-A1 ANTISENSE NUCLEIC ACIDS UTRN, RBM17, UPF1 HINT1 2785/4885GSK3A 3807/4885RPS6KA3 3160/4885
US-20210179659-A1 ANTISENSE NUCLEIC ACIDS UTRN, RBM17, UPF1 HINT1 3077/4885GSK3A 3983/4885RPS6KA3 3002/4885
US-10870676-B2 Antisense nucleic acids UTRN, RBM17, UPF1 HINT1 3077/4885GSK3A 3983/4885RPS6KA3 3002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.