Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | KDM5A | P29375 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5075662 | 0.94 | CA2 (0.45) | CCKBRCA2CA1LMNADNM1 | |
| SCHEMBL5081666 | 0.91 | DNM1 (0.44) | CCKBRCA2CA1LMNADNM1 | |
| SCHEMBL5078876 | 0.87 | CYP3A4 (0.58) | CA2CA1LMNAALDH1A1CYP3A4 | |
| SCHEMBL5078285 | 0.85 | CA2 (0.44) | CCKBRCA2CA1LMNADNM1 | |
| SCHEMBL5078272 | 0.84 | CYP3A4 (0.47) | CCKBRCA2CA1LMNAALDH1A1 | |
| SCHEMBL5078872 | 0.82 | CYP3A4 (0.61) | CA2CA1LMNAALDH1A1CYP3A4 | |
| SCHEMBL15400130 | 0.80 | CA2 (0.50) | CA2CA1LMNACYP3A4TSHR | |
| SCHEMBL27494955 | 0.79 | CA2 (0.48) | CA2CA1DNM1MAPK1 | |
| SCHEMBL25545057 | 0.78 | CYP3A4 (0.53) | LMNADNM1ALDH1A1CYP3A4TSHR | |
| SCHEMBL5078874 | 0.78 | DNM1 (0.46) | CCKBRKDM5ALMNADNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080319015-A1 | Insect Repellent Mixture | MERCK PATENT GESELLSCHAFT (DE) | 2008-12-25 | — | — | US | claimed |
| US-20070141014-A1 | Formulation assistants | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2007-06-21 | — | — | US | claimed |
| US-20080319015-A1 | Insect Repellent Mixture | MERCK PATENT GESELLSCHAFT (DE) | 2008-12-25 | — | — | US | disclosed |
| US-20070141014-A1 | Formulation assistants | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070141014-A1 | Formulation assistants | C1S, C1R, AKR1C3 | CCKBR 1981/4885CA2 2413/4885CA1 3226/4885 |
| US-20080319015-A1 | Insect Repellent Mixture | DDT, BCHE, DNPH1 | CCKBR 1341/4885CA2 451/4885CA1 1282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.