Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5081666 | 0.95 | DNM1 (0.44) | CA2CA1DNM1CYP3A4TSHR | |
| SCHEMBL5075662 | 0.90 | CA2 (0.45) | CA2CA1DNM1CYP3A4TSHR | |
| SCHEMBL5077570 | 0.87 | TSHR (0.46) | CA2CA1DNM1CYP3A4TSHR | |
| SCHEMBL5078872 | 0.85 | CYP3A4 (0.61) | CA2CA1CYP3A4TSHRATM | |
| SCHEMBL5075616 | 0.85 | CCKBR (0.45) | CA2CA1DNM1CYP3A4TSHR | |
| SCHEMBL5078876 | 0.81 | CYP3A4 (0.58) | CA2CA1CYP3A4TSHRATM | |
| SCHEMBL5087449 | 0.80 | CA2 (0.52) | CA2CA1MAPK1ALDH1A1 | |
| SCHEMBL5078272 | 0.77 | CYP3A4 (0.47) | CA2CA1CYP3A4TSHRATM | |
| SCHEMBL5078873 | 0.77 | DNM1 (0.47) | CA1DNM1TSHRATMDGKA | |
| SCHEMBL10013916 | 0.77 | CA2 (0.48) | CA2CA1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080319015-A1 | Insect Repellent Mixture | MERCK PATENT GESELLSCHAFT (DE) | 2008-12-25 | — | — | US | claimed |
| US-20070141014-A1 | Formulation assistants | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2007-06-21 | — | — | US | claimed |
| US-20080319015-A1 | Insect Repellent Mixture | MERCK PATENT GESELLSCHAFT (DE) | 2008-12-25 | — | — | US | disclosed |
| US-20070141014-A1 | Formulation assistants | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070141014-A1 | Formulation assistants | C1S, C1R, AKR1C3 | CA2 2413/4885CA1 3226/4885DNM1 4383/4885 |
| US-20080319015-A1 | Insect Repellent Mixture | DDT, BCHE, DNPH1 | CA2 451/4885CA1 1282/4885DNM1 2823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.