Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15131571 | 0.89 | F2 (0.55) | ALDH1A1GFERMEN1KMT2AMGLL | |
| SCHEMBL15131563 | 0.85 | HSP90AA1 (0.50) | ALDH1A1GFERMEN1KMT2AMGLL | |
| SCHEMBL15131565 | 0.85 | MAPT (0.57) | ALDH1A1GFERMEN1KMT2AMGLL | |
| SCHEMBL17717922 | 0.82 | NPC1 (0.38) | ALDH1A1GFERMEN1KMT2ALMNA | |
| SCHEMBL15131560 | 0.82 | EP300 (0.50) | ALDH1A1MEN1KMT2AMGLLLMNA | |
| SCHEMBL1639996 | 0.81 | ALDH1A1 (0.42) | ALDH1A1GFERMEN1KMT2AMGLL | |
| SCHEMBL15131564 | 0.79 | MEN1 (0.45) | ALDH1A1MEN1KMT2AMGLLGAA | |
| SCHEMBL15131573 | 0.79 | NPSR1 (0.51) | ALDH1A1MEN1KMT2AGAATP53 | |
| SCHEMBL3498051 | 0.78 | ALDH1A1 (0.50) | ALDH1A1GFERMEN1KMT2AMGLL | |
| SCHEMBL208852 | 0.77 | MEN1 (0.44) | ALDH1A1GFERMEN1KMT2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081576-A2 | METHOD OF IMPROVING BIOAVAILABILITY FOR NON-SEDATING BARBITURATES | Taro Pharmaceuticals North America, Inc. (KY) | 2009-07-29 | — | — | EP | claimed |
| WO-2008066704-A2 | METHOD OF IMPROVING BIOAVAILABILITY FOR NON-SEDATING BARBITURATES | TARO PHARMACEUTICALS NORTH AMERICA, INC. (KY) | 2008-06-05 | — | — | WO | claimed |
| US-20080132529-A1 | Method of improving bioavailability for non-sedating barbiturates | TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-06-05 | — | — | US | claimed |
| CN-1291720-C | Non-sedating barbituric acid derivatives | TARO PHARMA IND (IL) | 2006-12-27 | — | — | CN | claimed |
| EP-1485101-A4 | NON-SEDATING BARBITURIC ACID DERIVATIVES | TARO PHARMA IND (IL) | 2006-04-12 | — | — | EP | claimed |
| US-6939873-B2 | Non-sedating barbituric acid derivatives | TARO PHARMACEUTICALS INDUSTRIES LIMITED (IL) | 2005-09-06 | — | — | US | claimed |
| CN-1625401-A | Non-sedating barbituric acid derivatives | TARO PHARMA IND (IL) | 2005-06-08 | — | — | CN | claimed |
| EP-1485101-A1 | NON-SEDATING BARBITURIC ACID DERIVATIVES | Taro Pharmaceutical Industries Limited (IL) | 2004-12-15 | — | — | EP | claimed |
| US-20030187005-A1 | Non-sedating barbituric acid derivatives | TARO PHARMACEUTICAL INDUSTRIES LTD. | 2003-10-02 | — | — | US | claimed |
| WO-2003063872-A1 | NON-SEDATING BARBITURIC ACID DERIVATIVES | TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-08-07 | — | — | WO | claimed |
| CN-104744732-B | Optical film, polarizing plate and liquid crystal display device using the same, and compound | 富士胶片株式会社 | 2020-03-03 | — | — | CN | disclosed |
| US-10240033-B2 | Optical film and method for manufacturing same, polarization plate, and liquid crystal display apparatus | FUJIFILM CORPORATION (JP) | 2019-03-26 | — | — | US | disclosed |
| US-20170322358-A1 | POLARIZING PLATE, FRONT PANEL OF DISPLAY DEVICE, DISPLAY APPARATUS, SUBSTRATE OF TOUCH PANEL, RESISTIVE FILM-TYPE TOUCH PANEL, AND CAPACITANCE-TYPE TOUCH PANEL | FUJIFILM CORPORATION (JP) | 2017-11-09 | — | — | US | disclosed |
| US-20170322358-A1 | POLARIZING PLATE, FRONT PANEL OF DISPLAY DEVICE, DISPLAY APPARATUS, SUBSTRATE OF TOUCH PANEL, RESISTIVE FILM-TYPE TOUCH PANEL, AND CAPACITANCE-TYPE TOUCH PANEL | FUJIFILM CORPORATION (JP) | 2017-11-09 | — | — | US | disclosed |
| WO-2016190105-A1 | POLYIMIDE FILM, METHOD FOR PRODUCING POLYIMIDE FILM, FLEXIBLE PRINTED BOARD, SUBSTRATE FOR FLEXIBLE DISPLAYS, FRONT PLATE FOR FLEXIBLE DISPLAYS, LED LIGHTING DEVICE AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE | コニカミノルタ株式会社 | 2016-12-01 | — | — | WO | disclosed |
| US-6939873-B2 | Non-sedating barbituric acid derivatives | TARO PHARMACEUTICALS INDUSTRIES LIMITED (IL) | 2005-09-06 | — | — | US | disclosed |
| CN-1625401-A | Non-sedating barbituric acid derivatives | TARO PHARMA IND (IL) | 2005-06-08 | — | — | CN | disclosed |
| EP-1485101-A1 | NON-SEDATING BARBITURIC ACID DERIVATIVES | Taro Pharmaceutical Industries Limited (IL) | 2004-12-15 | — | — | EP | disclosed |
| US-20030187005-A1 | Non-sedating barbituric acid derivatives | TARO PHARMACEUTICAL INDUSTRIES LTD. | 2003-10-02 | — | — | US | disclosed |
| WO-2003063872-A1 | NON-SEDATING BARBITURIC ACID DERIVATIVES | TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132529-A1 | Method of improving bioavailability for non-sedating barbiturates | MTNR1B, GABRB3, GABBR1 | ALDH1A1 790/4885GFER 3151/4885MEN1 1891/4885 |
| US-20030187005-A1 | Non-sedating barbituric acid derivatives | GABRA5, GABRA1, GABRA3 | ALDH1A1 283/4885GFER 3680/4885MEN1 3949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.