SCHEMBL5076286

SCHEMBL5076286

CC(=O)OC/C=C/C[PH](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
AKT1 P31749 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.33
TK1 P04183 2/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SLC18A3 Q16572 2/20 0.32
MAPK1 P28482 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP12 P39900 1/20 0.31
TSHR P16473 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5076288 1.00 ALDH1A1 (0.43) ALDH1A1AKT1SMN1; SMN2TK1NPC1
SCHEMBL5076304 0.82 ALDH1A1 (0.39) ALDH1A1AKT1TK1MAPTL3MBTL1
SCHEMBL5076302 0.82 ALDH1A1 (0.39) ALDH1A1AKT1TK1MAPTL3MBTL1
SCHEMBL6915714 0.81 ALDH1A1 (0.38) ALDH1A1AKT1TK1MEN1KMT2A
SCHEMBL5076228 0.77 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2MAPTSLC18A3TSHR
SCHEMBL5076230 0.77 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2MAPTSLC18A3TSHR
SCHEMBL5074262 0.76 MAOB (0.38) CYP1A2
SCHEMBL17428430 0.76 MAOB (0.38) CYP1A2
SCHEMBL7590667 0.75 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2NPC1MAPTHPGD
SCHEMBL10325277 0.75 ALDH1A1 (0.56) ALDH1A1KMT2AMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7423168-B2 Reacting allyl starting compound with oxygen nucleophilic agent in presence of transition metal catalyst and monodentate phosphite MITSUBISHI CHEMICAL CORPORATION (JP) 2008-09-09 US disclosed
US-7241857-B2 Method for producing allyl compound, and ether or ester compound produced thereby MITSUBISHI CHEMICAL CORPORATION (JP) 2007-07-10 US disclosed
US-7173157-B2 Method for producing an allyl compound MITSUBISHI CHEMICAL CORPORATION (JP) 2007-02-06 US disclosed
US-7119222-B2 Method for producing allyl compound, and ether or ester compound produced thereby MITSUBISHI CHEMICAL CORPORATION (JP) 2006-10-10 US disclosed
US-20060106181-A1 Method for producing allyl compound, and ether or ester compound produced thereby MITSUBISHI CHEMICAL CORPORATION (JP) 2006-05-18 US disclosed
US-20050075518-A1 Method for producing allyl compound, and allyl compound produced thereby MITSUBISHI CHEMICAL CORPORATION (JP) 2005-04-07 US disclosed
US-20040147757-A1 Method for producing allyl compound, and ether or ester compound produced thereby MITSUBISHI CHEMICAL CORPORATION (JP) 2004-07-29 US disclosed
US-20040092777-A1 Method for producing allyl compound MITSUBISHI CHEMICAL CORPORATION (JP) 2004-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060106181-A1 Method for producing allyl compound, and ether or ester compound produced thereby AGPAT5, TST, AGPAT2 ALDH1A1 1665/4885AKT1 613/4885SMN1; SMN2 3127/4885
US-20040147757-A1 Method for producing allyl compound, and ether or ester compound produced thereby AGPAT5, TST, AGPAT2 ALDH1A1 1665/4885AKT1 613/4885SMN1; SMN2 3127/4885
US-20040092777-A1 Method for producing allyl compound CCNT1, APEX1, REV1 ALDH1A1 636/4885AKT1 557/4885SMN1; SMN2 2217/4885
US-20050075518-A1 Method for producing allyl compound, and allyl compound produced thereby CCNT1, AOC3, ATL3 ALDH1A1 790/4885AKT1 246/4885SMN1; SMN2 2960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.