Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.60 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.60 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.60 |
| ▸ | PRKCG | P05129 | 1/20 | 0.60 |
| ▸ | PRKACA | P17612 | 1/20 | 0.60 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | AKT1 | P31749 | 1/20 | 0.60 |
| ▸ | GSK3A | P49840 | 1/20 | 0.60 |
| ▸ | GSK3B | P49841 | 1/20 | 0.60 |
| ▸ | PRKX | P51817 | 1/20 | 0.60 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.60 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.60 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.60 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.60 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.60 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28173164 | 0.86 | HDAC6 (0.58) | HPGDSSMN1; SMN2ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL7705627 | 0.83 | RAB9A (0.73) | SMN1; SMN2HDAC6HDAC2HDAC8RAB9A | |
| SCHEMBL354041 | 0.83 | TSHR (0.76) | HPGDSSMN1; SMN2ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL5083050 | 0.83 | L3MBTL1 (0.69) | SMN1; SMN2ROCK2L3MBTL1LMNA | |
| SCHEMBL5083115 | 0.83 | TSHR (0.71) | SMN1; SMN2HDAC6HDAC2SCN2ASCN10A | |
| Iodide SCHEMBL15903217 | 0.82 | TSHR (0.74) | HPGDSSMN1; SMN2ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL5078937 | 0.82 | EPHX2 (0.60) | HPGDSSMN1; SMN2ROCK2RPS6KA5MAP4K4 | |
| SCHEMBL17101816 | 0.82 | NPC1 (0.53) | HPGDSSMN1; SMN2ROCK2PRKACAGSK3A | |
| SCHEMBL11900090 | 0.81 | HDAC6 (0.85) | ROCK2RPS6KA5MAP4K4PRKCGPRKACA | |
| SCHEMBL457082 | 0.81 | HDAC6 (0.79) | ROCK2RPS6KA5MAP4K4PRKCGPRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715807-A | Secretory immunoglobulin A (sIgA) -binding nucleic acid molecule, sensor for sIgA analysis, and sIgA analysis method | 日本电气方案创新株式会社 | 2019-05-03 | — | — | CN | disclosed |
| US-20080132505-A1 | Combination Of Cb2 Modulators And Pde4 Inhibitors For Use In Medicine | GLAXO GROUP LIMITED | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132505-A1 | Combination Of Cb2 Modulators And Pde4 Inhibitors For Use In Medicine | CNR2, CNR1, PDE4A | HPGDS 387/4885SMN1; SMN2 3540/4885ROCK2 1040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.