⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575180 | 0.80 | — | — | |
| SCHEMBL704114 | 0.78 | — | — | |
| SCHEMBL705779 | 0.76 | ADRB2 (0.39) | — | |
| SCHEMBL707612 | 0.76 | — | — | |
| SCHEMBL14321215 | 0.74 | ADRB2 (0.38) | — | |
| SCHEMBL2027834 | 0.73 | TSHR (0.31) | — | |
| SCHEMBL15309363 | 0.73 | — | — | |
| SCHEMBL14321065 | 0.72 | THRB (0.40) | — | |
| SCHEMBL31286323 | 0.72 | THRB (0.40) | — | |
| SCHEMBL705064 | 0.71 | ADRB2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174743-A1 | TIRE TREAD RUBBER COMPOSITION COMPRISING RICE HUSK ASH SILICA | THE GOODYEAR TIRE & RUBBER COMPANY | 2023-06-08 | — | — | US | disclosed |
| US-7417084-B2 | Rubber compound containing an organothiosulfate and a bismaleimide | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2008-08-26 | — | — | US | disclosed |
| US-7261929-B2 | Vulcanized rubber with steel strands | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2007-08-28 | — | — | US | disclosed |
| US-6727374-B2 | TRIALKOXYSILYLHYDROCARBYL CYCLOHEXYL DISULFIDE, MADE BY REACTING N-CYCLOHEXYLTHIOPHTHALIMIDE AND A MERCAPTOALKOXYSILANE; SULFUR VULCANIZED RUBBER TIRES, BELTS AND HOSES | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-04-27 | — | — | US | disclosed |
| US-6569942-B2 | Pneumatic tires | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-05-27 | — | — | US | disclosed |
| US-20030050370-A1 | Silica filled multi-viscoelastic response rubber | VICTOR THIELEN GEORGES MARCEL (LU) | 2003-03-13 | — | — | US | disclosed |
| US-20010056142-A1 | Asymmetrical siloxy disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY. | 2001-12-27 | — | — | US | disclosed |