⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2027834 | 0.93 | TSHR (0.31) | — | |
| SCHEMBL707612 | 0.82 | — | — | |
| SCHEMBL705779 | 0.82 | ADRB2 (0.39) | — | |
| SCHEMBL14321215 | 0.80 | ADRB2 (0.38) | — | |
| SCHEMBL5077487 | 0.80 | — | — | |
| SCHEMBL31286323 | 0.78 | THRB (0.40) | — | |
| SCHEMBL14321065 | 0.78 | THRB (0.40) | — | |
| SCHEMBL23071170 | 0.76 | CYP3A4 (0.36) | — | |
| SCHEMBL3135710 | 0.76 | DNM1 (0.42) | — | |
| SCHEMBL5321508 | 0.75 | THRB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465670-B2 | SURFACE TREATMENT USING ORGANOSILICON COMPOUND, SOLVENT AND PHASE TRANSFER CATALYST | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-10-15 | — | — | US | claimed |
| US-20020022085-A1 | Preparation of surface modified silica | GOODYEAR TIRE & RUBBER COMPANY, THE | 2002-02-21 | — | — | US | claimed |
| CN-101809078-B | Rubber compositions | CHEMTURA CORP | 2013-06-12 | — | — | CN | disclosed |
| CN-102115552-B | Pneumatic tire | GOODYEAR TIRE & RUBBER | 2013-06-12 | — | — | CN | disclosed |
| CN-101148521-B | Pneumatic tire | THE GOODYEAR TIRE & RUBBER CO. (US) | 2012-02-08 | — | — | CN | disclosed |
| CN-102115552-A | Pneumatic tire | GOODYEAR TIRE & RUBBER | 2011-07-06 | — | — | CN | disclosed |
| CN-102070797-A | Pneumatic tire | GOODYEAR TIRE & RUBBER | 2011-05-25 | — | — | CN | disclosed |
| CN-1886451-B | Rubber compositions and methods for decreasing the tangent delta value and abrasion index | UNIROYAL CHEM CO INC | 2011-01-26 | — | — | CN | disclosed |
| CN-101809078-A | Rubber combination | CHEMTURA CORP | 2010-08-18 | — | — | CN | disclosed |
| CN-100513475-C | Pneumatic tire with sidewall component containing high strength glass bubbles | GOODYEAR TIRE & RUBBER (US) | 2009-07-15 | — | — | CN | disclosed |
| CN-101157786-A | Pneumatic tire | GOODYEAR TIRE & RUBBER (US) | 2008-04-09 | — | — | CN | disclosed |
| EP-0839816-B1 | The preparation of sulfur-containing organosilicon compounds | GOODYEAR TIRE & RUBBER (US) | 2004-04-28 | — | — | EP | disclosed |
| EP-0794186-B1 | The preparation of sulfur-containing organosilicon compounds | GOODYEAR TIRE & RUBBER (US) | 2003-05-28 | — | — | EP | disclosed |
| EP-1178077-A1 | The preparation of surface modified silica | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-02-06 | — | — | EP | disclosed |
| CN-1245176-A | Inflatable tyre with tread containing resin | GOODYEAR TIRE & RUBBER (US) | 2000-02-23 | — | — | CN | disclosed |
| CN-1240802-A | Rubber Compositions containing stearyl acrylate or methacrylate | GOODYEAR TIRE & RUBBER (US) | 2000-01-12 | — | — | CN | disclosed |
| CN-1240801-A | Rubber compositions containing carboxymaleimidophenyl ester | GOODYEAR TIRE & RUBBER (US) | 2000-01-12 | — | — | CN | disclosed |
| EP-0839816-A1 | The preparation of sulfur-containing organosilicon compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0794186-A1 | The preparation of sulfur-containing organosilicon compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-10 | — | — | EP | disclosed |
| US-5663396-A | Preparation of sulfur-containing organosilicon compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-02 | — | — | US | disclosed |