Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3141130 | 0.75 | THRB (0.57) | THRATHRB | |
| SCHEMBL3145340 | 0.71 | THRA (0.55) | THRATHRB | |
| SCHEMBL5074393 | 0.70 | KDM4E (0.37) | THRATHRB | |
| SCHEMBL3142092 | 0.70 | KDM4E (0.46) | THRATHRB | |
| SCHEMBL3140997 | 0.69 | THRA (0.55) | THRATHRB | |
| SCHEMBL3137537 | 0.69 | PTPN7 (0.44) | THRATHRB | |
| SCHEMBL3137369 | 0.68 | THRA (0.56) | THRATHRB | |
| SCHEMBL3135791 | 0.67 | KDM4E (0.43) | THRATHRB | |
| SCHEMBL3135783 | 0.67 | KDM4E (0.43) | THRATHRB | |
| SCHEMBL23062670 | 0.66 | KDM4E (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899309-A1 | HETEROCYCLIC COMPOUNDS AS AGONISTS FOR THE THYROID RECEPTOR | KARO BIO AB (SE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007003419-A1 | HETEROCYCLIC COMPOUNDS AS AGONISTS FOR THE THYROID RECEPTOR | KARO BIO AB (SE) | 2007-01-11 | — | — | WO | disclosed |