Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23062670 | 0.78 | KDM4E (0.53) | — | |
| SCHEMBL29612481 | 0.78 | KDM4E (0.53) | — | |
| SCHEMBL2495171 | 0.76 | KDM4E (0.55) | — | |
| SCHEMBL29518650 | 0.76 | KDM4E (0.55) | — | |
| SCHEMBL2785190 | 0.76 | THRB (0.71) | THRBTHRA | |
| SCHEMBL23042415 | 0.76 | HTT (0.43) | — | |
| SCHEMBL3137537 | 0.75 | PTPN7 (0.44) | THRBTHRA | |
| SCHEMBL12585461 | 0.75 | THRB (0.73) | THRBTHRA | |
| SCHEMBL3137369 | 0.74 | THRA (0.56) | THRBTHRA | |
| SCHEMBL5858273 | 0.74 | THRA (0.58) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004271-A1 | HETEROCYCLIC COMPOUNDS AS AGANIST FOR THE THYROID RECEPTOR | KARO BIO AB (SE) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004271-A1 | HETEROCYCLIC COMPOUNDS AS AGANIST FOR THE THYROID RECEPTOR | TSHR, GHSR, TRHR | THRB 6/4885THRA 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.