Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.87 |
| ▸ | ALDH2 | P05091 | 4/20 | 0.87 |
| ▸ | LMNA | P02545 | 3/20 | 0.87 |
| ▸ | HTT | P42858 | 3/20 | 0.87 |
| ▸ | TP53 | P04637 | 3/20 | 0.87 |
| ▸ | HPGD | P15428 | 3/20 | 0.87 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.87 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.87 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.87 |
| ▸ | FAAH | O00519 | 3/20 | 0.87 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.87 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.87 |
| ▸ | FBP1 | P09467 | 2/20 | 0.87 |
| ▸ | MAPT | P10636 | 2/20 | 0.87 |
| ▸ | PKM | P14618 | 2/20 | 0.87 |
| ▸ | LOX | P28300 | 2/20 | 0.87 |
| ▸ | LOXL3 | P58215 | 2/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.87 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiram SCHEMBL21144 | 0.93 | ALDH1A1 (1.00) | MGLLALDH1A1ALDH2LMNAHTT | |
| Thiram SCHEMBL1216571 | 0.93 | ALDH1A1 (1.00) | MGLLALDH1A1ALDH2LMNAHTT | |
| Thiram SCHEMBL305889 | 0.90 | ALDH1A1 (0.81) | MGLLALDH1A1ALDH2LMNAHTT | |
| Thiram SCHEMBL3741643 | 0.90 | ALDH1A1 (0.93) | MGLLALDH1A1ALDH2LMNAHTT | |
| Thiram SCHEMBL10884509 | 0.90 | ALDH1A1 (0.93) | MGLLALDH1A1ALDH2LMNAHTT | |
| Thiram SCHEMBL23248447 | 0.90 | ALDH1A1 (0.93) | MGLLALDH1A1ALDH2LMNAHTT | |
| Thiram SCHEMBL2773352 | 0.90 | ALDH1A1 (0.93) | MGLLALDH1A1ALDH2LMNAHTT | |
| Thiram SCHEMBL10881913 | 0.90 | ALDH1A1 (0.93) | MGLLALDH1A1ALDH2LMNAHTT | |
| Thiram SCHEMBL10883678 | 0.90 | ALDH1A1 (0.93) | MGLLALDH1A1ALDH2LMNAHTT | |
| Thiram SCHEMBL234787 | 0.90 | ALDH1A1 (0.93) | MGLLALDH1A1ALDH2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053400-A | PRECIPITATION WITH AN ALKYLTHIURAM SULFIDE COMPOUND | THE METALUX CORPORATION (US) | 1977-10-11 | — | — | US | claimed |
| US-20230115675-A1 | METHODS OF TREATING CANCER | BROAD INST INC (US) | 2023-04-13 | — | — | US | disclosed |
| EP-4111202-A1 | METHODS OF TREATING CANCER | The Broad Institute Inc. (US) | 2023-01-04 | — | — | EP | disclosed |
| US-20190119057-A1 | PAPER FEEDING ROLL | SUMITOMO RIKO COMPANY LIMITED (JP) | 2019-04-25 | — | — | US | disclosed |
| US-7335707-B2 | For pneumatic tire containing 4-phenyl isocyanate and sulfur as crosslinking material, with increased filler/reinforcing material loading; improved green strength, aged flex life, tear, and reversion resistance | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2008-02-26 | — | — | US | disclosed |
| US-20070100030-A1 | Barrier layer composition | THE GOODYEAR TIRE & RUBBER COMPANY | 2007-05-03 | — | — | US | disclosed |
| EP-0504320-B1 | METHOD FOR PREPARING STERICALLY HINDERED ARYL PHOSPHITES | UNIROYAL CHEM CO INC (US) | 1994-09-21 | — | — | EP | disclosed |
| US-5254709-A | Catalytic reaction of phosphorus trihalide with a phenolic compound | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0504320-A1 | METHOD FOR PREPARING STERICALLY HINDERED ARYL PHOSPHITES. | UNIROYAL CHEM CO INC (US) | 1992-09-23 | — | — | EP | disclosed |
| WO-1991009040-A1 | METHOD FOR PREPARING STERICALLY HINDERED ARYL PHOSPHITES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1991-06-27 | — | — | WO | disclosed |
| US-4774288-A | PHENOLIC RESIN VULCANIZATION SYSTEM | POLYSAR LIMITED (CA) | 1988-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230115675-A1 | METHODS OF TREATING CANCER | SOD1, RNASE1, COXFA4L2 | MGLL 3712/4885ALDH1A1 727/4885ALDH2 185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.