Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335603 | 0.92 | POLB (0.37) | POLBTAAR1SLC6A4HTTAOC3 | |
| SCHEMBL7699622 | 0.92 | KMT2A (0.42) | POLBTAAR1SLC6A4ALDH1A1MITF | |
| SCHEMBL335496 | 0.88 | TAAR1 (0.56) | TAAR1SLC6A4ALDH1A1LMNAHTT | |
| SCHEMBL6912043 | 0.83 | ADRB2 (0.41) | SLC6A4ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL4379785 | 0.82 | TAAR1 (0.50) | TAAR1SLC6A4ALDH1A1LMNAHTT | |
| SCHEMBL4379781 | 0.82 | TAAR1 (0.50) | TAAR1SLC6A4ALDH1A1LMNAHTT | |
| SCHEMBL19317395 | 0.82 | TRPA1 (0.53) | POLBTAAR1ALDH1A1AOC3KDM4E | |
| SCHEMBL17071841 | 0.74 | NPC1 (0.47) | SLC6A4ALDH1A1MITFLMNAMAPT | |
| SCHEMBL12846949 | 0.74 | NPC1 (0.47) | SLC6A4ALDH1A1MITFLMNAMAPT | |
| SCHEMBL17069342 | 0.74 | NPC1 (0.47) | SLC6A4ALDH1A1MITFLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141049-B1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION | BASELL POLYOLEFINE GMBH (DE) | 2004-06-09 | — | — | EP | claimed |
| US-20080139762-A1 | Metallocene Compounds, Ligands Used in Their Preparation, Preparation of 1-Butene Polymers and 1-Butene Polymers Therefrom | BASELL POLYOLEFINE GMBH (DE) | 2008-06-12 | — | — | US | disclosed |
| US-20080027190-A1 | Process for Producing Fractionable 1-Butene Polymers | BASELL POLYOLEFINE GMBH (DE) | 2008-01-31 | — | — | US | disclosed |
| EP-1222216-B1 | PROPYLENE POLYMERS AND PROCESS FOR THE PREPARATION THEREOF | BASELL POLYOLEFINE GMBH (DE) | 2004-12-29 | — | — | EP | disclosed |
| EP-1141049-B1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION | BASELL POLYOLEFINE GMBH (DE) | 2004-06-09 | — | — | EP | disclosed |
| US-6703457-B2 | A POLYMERIZATION CATALYST SYSTEM CONTAINING A BRIDGED METALLOCENE AND A SUITABLE ACTIVATING COCATALYST; REDUCING THE CONCENTRATION OF HYDROGEN FORMED DURING POLYMERIZATION IS REDUCED BY MEANS OF HYDROGENATION CATALYST | BASELL POLYOLEFINE GMBH (DE) | 2004-03-09 | — | — | US | disclosed |
| US-20030130445-A1 | Propylene polymers and process for the preparation thereof | BASELL POLYOLEFINE GMBH (DE) | 2003-07-10 | — | — | US | disclosed |
| EP-1222216-A1 | PROPYLENE POLYMERS AND PROCESS FOR THE PREPARATION THEREOF | Basell Technology Company B.V. (NL) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001090205-A1 | PROPYLENE POLYMERS AND PROCESS FOR THE PREPARATION THEREOF | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2001-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139762-A1 | Metallocene Compounds, Ligands Used in Their Preparation, Preparation of 1-Butene Polymers and 1-Butene Polymers Therefrom | CHRM1, B2M, CHRM2 | POLB 1890/4885TAAR1 586/4885SLC6A4 4857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.