Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699622 | 0.93 | KMT2A (0.42) | ADRB2MEN1KMT2AC3AR1SLC6A3 | |
| SCHEMBL335603 | 0.90 | POLB (0.37) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL335853 | 0.90 | ADRB2 (0.48) | ADRB2C3AR1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL5078508 | 0.83 | POLB (0.47) | KMT2ASLC6A4MAPTALDH1A1NPC1 | |
| SCHEMBL5109245 | 0.82 | ADRB2 (0.45) | ADRB2MEN1KMT2AC3AR1SLC6A3 | |
| SCHEMBL6027378 | 0.78 | IDO1 (0.40) | ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7122909 | 0.76 | PGR (0.39) | ADRB2MEN1KMT2AC3AR1SLC6A3 | |
| SCHEMBL6935122 | 0.76 | ADRB2 (0.50) | ADRB2MEN1KMT2AP2RX3SLC6A4 | |
| SCHEMBL5109242 | 0.73 | POLB (0.40) | ADRB2MEN1KMT2ASLC6A3CNR1 | |
| SCHEMBL21910182 | 0.72 | TSHR (0.48) | ADRB2MEN1KMT2ASLC6A3P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6703458-B2 | COORDINATION CATALYSTS; SPHERICAL MORPHOLOGY | BASELL POLYOLEFINE GMBH (DE) | 2004-03-09 | — | — | US | disclosed |
| US-20030018146-A1 | Catalyst components for the polymerization of olefins | EQUISTAR CHEMICALS, LP | 2003-01-23 | — | — | US | disclosed |