Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6912043 | 0.93 | ADRB2 (0.41) | KMT2AMEN1C3AR1SLC6A4ALDH1A1 | |
| SCHEMBL5078508 | 0.92 | POLB (0.47) | KMT2APOLBSLC6A4TAAR1MITF | |
| SCHEMBL335603 | 0.84 | POLB (0.37) | POLBSLC6A4TAAR1HTTIDO1 | |
| SCHEMBL335853 | 0.84 | ADRB2 (0.48) | POLBC3AR1SLC6A4LMNAIDO1 | |
| SCHEMBL335496 | 0.80 | TAAR1 (0.56) | KMT2AMEN1SLC6A4TAAR1ALDH1A1 | |
| SCHEMBL7122909 | 0.77 | PGR (0.39) | KMT2AMEN1POLBC3AR1SLC6A4 | |
| SCHEMBL5109245 | 0.77 | ADRB2 (0.45) | KMT2AMEN1C3AR1SLC6A4MAPT | |
| SCHEMBL18676704 | 0.75 | RIPK1 (0.53) | KMT2AMEN1C3AR1SLC6A4TAAR1 | |
| SCHEMBL4379781 | 0.75 | TAAR1 (0.50) | KMT2AMEN1SLC6A4TAAR1ALDH1A1 | |
| SCHEMBL19317395 | 0.75 | TRPA1 (0.53) | POLBTAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395668-B1 | COORDINATION CATALYSTS | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-05-28 | — | — | US | claimed |
| EP-1141049-A1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION | Basell Technology Company B.V. (NL) | 2001-10-10 | — | — | EP | claimed |
| WO-2000035974-A1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2000-06-22 | — | — | WO | claimed |
| US-6395668-B1 | COORDINATION CATALYSTS | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-05-28 | — | — | US | disclosed |