Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3679594 | 0.82 | GPR3 (0.32) | — | |
| SCHEMBL13825602 | 0.70 | MAOA (0.39) | HTR2CMAOAMAOBCHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL3655003 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL6230015 | 0.65 | CHRNB2 (0.33) | HTR2CCHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL15948324 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL616319 | 0.64 | — | — | |
| SCHEMBL3843765 | 0.64 | — | — | |
| Methane SCHEMBL9068644 | 0.64 | CHRNB2 (0.33) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL5355296 | 0.63 | ELANE (0.42) | — | |
| Hydrochloric Acid SCHEMBL3273189 | 0.63 | MAOA (0.37) | HTR2CMAOAMAOBCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964860-A1 | ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER | Tosoh Corporation (JP) | 2008-09-03 | — | — | EP | disclosed |