SCHEMBL5079269

SCHEMBL5079269

c1ccc(SN=C(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.38
MAPT P10636 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
HSD17B10 Q99714 2/20 0.38
MGLL Q99685 1/20 0.38
ALDH1A1 P00352 6/20 0.35
NPSR1 Q6W5P4 2/20 0.35
PLIN1 O60240 1/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
PLIN5 Q00G26 1/20 0.35
ABHD5 Q8WTS1 1/20 0.35
GFER P55789 1/20 0.35
ESR1 P03372 2/20 0.35
CES2 O00748 2/20 0.35
CES1 P23141 2/20 0.35
DAO P14920 1/20 0.35
TSHR P16473 1/20 0.35
NAPRT Q6XQN6 1/20 0.35
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5354641 0.77 LMNA (0.44) HPGDMAPTSMN1; SMN2HSD17B10MGLL
SCHEMBL3447542 0.77 LMNA (0.44) HPGDMAPTSMN1; SMN2HSD17B10MGLL
SCHEMBL3448599 0.73 HPGD (0.39) HPGDMAPTSMN1; SMN2HSD17B10MGLL
SCHEMBL28493100 0.73 HTR3A (0.42) HPGDMAPTSMN1; SMN2HSD17B10MGLL
SCHEMBL3272106 0.68 ALDH1A1 (0.52) HPGDMAPTSMN1; SMN2HSD17B10ALDH1A1
SCHEMBL9858411 0.68 HPGD (0.50) HPGDMAPTSMN1; SMN2HSD17B10MGLL
SCHEMBL19835528 0.67 TDP1 (0.38) HPGDMAPTSMN1; SMN2HSD17B10MGLL
SCHEMBL27961040 0.66 HPGD (0.64) HPGDMAPTSMN1; SMN2MGLLALDH1A1
SCHEMBL273196 0.66 HPGD (0.64) HPGDMAPTSMN1; SMN2MGLLALDH1A1
SCHEMBL6407219 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5332784-A Conjugated diene, vinylaromatic copolymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-07-26 US claimed
EP-1245585-B1 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR CORP (JP) 2008-05-21 EP disclosed
US-6838538-B2 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR CORPORATION (JP) 2005-01-04 US disclosed
US-20030100683-A1 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR CORPORATION (JP) 2003-05-29 US disclosed
EP-1245585-A2 Hydrogenated modified polymer, process for producing the same and composition containing the same JSR Corporation (JP) 2002-10-02 EP disclosed
EP-0473206-B1 Compositions containing a terminal-modified block copolymer ASAHI CHEMICAL IND (JP) 1999-06-23 EP disclosed
US-5332784-A Conjugated diene, vinylaromatic copolymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-07-26 US disclosed
EP-0473206-A2 Compositions containing a terminal-modified block copolymer Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-03-04 EP disclosed
EP-0245505-A1 TERMINAL-MODIFIED BLOCK COPOLYMER AND COMPOSITION CONTAINING SAID COPOLYMER Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-11-19 EP disclosed