SCHEMBL5354641

SCHEMBL5354641

C/C(=N/Sc1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP1A2 P05177 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MAPT P10636 2/20 0.42
CYP2D6 P10635 1/20 0.42
POLB P06746 1/20 0.42
ALDH1A1 P00352 3/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
GAA P10253 2/20 0.42
NFKB1 P19838 2/20 0.42
NFKB2 Q00653 2/20 0.42
RELA Q04206 2/20 0.42
KDM4E B2RXH2 1/20 0.42
OPRK1 P41145 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
CTSK P43235 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3447542 1.00 LMNA (0.44) LMNAMAPK1HTTL3MBTL1CYP1A2
SCHEMBL3448599 0.79 HPGD (0.39) MAPK1L3MBTL1HSD17B10MAPTALDH1A1
SCHEMBL12500429 0.77 KMT2A (0.48) LMNAMAPK1HTTL3MBTL1CYP1A2
SCHEMBL5079269 0.77 HPGD (0.38) LMNAMAPK1HTTCYP1A2HSD17B10
SCHEMBL14456620 0.72 LMNA (0.42) LMNAMAPK1HTTL3MBTL1CYP1A2
Diphenylsulfane SCHEMBL28010798 0.72 ALDH1A1 (0.52) LMNAMAPK1HTTL3MBTL1CYP1A2
SCHEMBL4279968 0.71 FURIN (0.56) LMNAMAPK1HTTL3MBTL1CYP1A2
SCHEMBL7968589 0.71 FURIN (0.56) LMNAMAPK1HTTL3MBTL1CYP1A2
SCHEMBL4037961 0.71 FURIN (0.56) LMNAMAPK1HTTL3MBTL1CYP1A2
SCHEMBL28493100 0.70 HTR3A (0.42) LMNAMAPK1CYP1A2HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5332784-A Conjugated diene, vinylaromatic copolymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-07-26 US claimed
EP-1316582-B1 POLYVINYL ALCOHOL RESIN COMPOSITION AND MULTILAYER PACKAGES KURARAY CO (JP) 2012-10-31 EP disclosed
US-7255904-B2 Polyvinyl alcohol resin composition and multilayer packages KURARAY CO., LTD. (JP) 2007-08-14 US disclosed
EP-1316582-A1 POLYVINYL ALCOHOL RESIN COMPOSITION AND MULTILAYER PACKAGES KURARAY CO., LTD. (JP) 2003-06-04 EP disclosed
US-20030022974-A1 Polyvinyl alcohol resin composition and multilayer packages KURARAY CO., LTD. (JP) 2003-01-30 US disclosed
EP-0473206-B1 Compositions containing a terminal-modified block copolymer ASAHI CHEMICAL IND (JP) 1999-06-23 EP disclosed
US-5332784-A Conjugated diene, vinylaromatic copolymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-07-26 US disclosed
EP-0473206-A2 Compositions containing a terminal-modified block copolymer Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-03-04 EP disclosed
EP-0245505-A1 TERMINAL-MODIFIED BLOCK COPOLYMER AND COMPOSITION CONTAINING SAID COPOLYMER Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-11-19 EP disclosed