Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4088281 | 0.63 | SLC6A3 (0.47) | SLC6A3SLC6A4SLC6A2LTA4H | |
| SCHEMBL19836865 | 0.60 | SLC6A3 (0.38) | SLC6A3 | |
| SCHEMBL1784442 | 0.58 | TAAR1 (0.60) | LTA4H | |
| SCHEMBL3592279 | 0.58 | LDHA (0.42) | SLC6A4LDHA | |
| SCHEMBL6479568 | 0.58 | LDHA (0.42) | SLC6A4LDHA | |
| SCHEMBL6330584 | 0.58 | ADRB2 (0.46) | LTA4H | |
| SCHEMBL6512842 | 0.57 | RAB9A (0.47) | LTA4H | |
| SCHEMBL8432804 | 0.57 | DRD4 (0.50) | LTA4H | |
| Hydrochloric Acid SCHEMBL6480630 | 0.57 | LDHA (0.41) | SLC6A4LDHA | |
| SCHEMBL1045800 | 0.57 | SLC6A4 (0.71) | SLC6A3SLC6A4SLC6A2KCNK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008133884-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | COMBINATORX, INCORPORATED (US) | 2008-11-06 | — | — | WO | disclosed |