Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FHIT | P49789 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5078848 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPTSMN1; SMN2GAA | |
| SCHEMBL17965795 | 0.80 | TSHR (0.50) | ALDH1A1TSHRMAPTSMN1; SMN2GAA | |
| SCHEMBL5078862 | 0.78 | FHIT (0.50) | ALDH1A1TSHRMAPTSMN1; SMN2GAA | |
| SCHEMBL5082910 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTSMN1; SMN2GAA | |
| SCHEMBL5077047 | 0.76 | ALDH1A1 (0.51) | ALDH1A1TSHRMAPTSMN1; SMN2GAA | |
| SCHEMBL6058847 | 0.75 | TSHR (0.39) | ALDH1A1TSHRMAPTSMN1; SMN2GSK3B | |
| SCHEMBL17965785 | 0.74 | ALDH1A1 (0.52) | ALDH1A1TSHRMAPTSMN1; SMN2HPGD | |
| SCHEMBL19795504 | 0.72 | TSHR (0.50) | ALDH1A1TSHRMAPTSMN1; SMN2GAA | |
| SCHEMBL8550024 | 0.71 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPTSMN1; SMN2HPGD | |
| SCHEMBL5080676 | 0.70 | TSHR (0.41) | ALDH1A1TSHRMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371802-B2 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2008-05-13 | — | — | US | disclosed |
| US-20070106039-A1 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2007-05-10 | — | — | US | disclosed |