Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082910 | 0.81 | ALDH1A1 (0.47) | TSHRALDH1A1GPR35MAPTNPC1 | |
| SCHEMBL5078848 | 0.74 | ALDH1A1 (0.41) | TSHRALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL5078862 | 0.72 | FHIT (0.50) | TSHRALDH1A1GPR35MAPTNPC1 | |
| SCHEMBL5079631 | 0.70 | ALDH1A1 (0.47) | TSHRALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL5082934 | 0.70 | ALDH1A1 (0.51) | TSHRALDH1A1GPR35MAPTNPC1 | |
| SCHEMBL5077042 | 0.70 | ALDH1A1 (0.51) | TSHRALDH1A1GPR35MAPTNPC1 | |
| SCHEMBL6058847 | 0.69 | TSHR (0.39) | TSHRALDH1A1GPR35MAPTCACNA1F | |
| SCHEMBL4737610 | 0.68 | ALDH1A1 (0.58) | TSHRALDH1A1MAPTRAB9ATDP1 | |
| SCHEMBL11481513 | 0.68 | ALDH1A1 (0.49) | TSHRALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL17965785 | 0.67 | ALDH1A1 (0.52) | TSHRALDH1A1GPR35MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371802-B2 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2008-05-13 | — | — | US | disclosed |
| US-20070106039-A1 | Components and catalysts for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2007-05-10 | — | — | US | disclosed |
| EP-1678218-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005047351-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2005-05-26 | — | — | WO | disclosed |